Nanoparticle-based delivery system for application of siRNA in vivo
Y Wang, Z Li, Y Han, L Hwa Liang… - Current drug …, 2010 - ingentaconnect.com
Small interfering RNAs (siRNAs) silence the expression of specific target genes by
mediating RNA interference (RNAi) in mammalian cells. siRNAs have not only been widely …
mediating RNA interference (RNAi) in mammalian cells. siRNAs have not only been widely …
Research progress on siRNA delivery with nonviral carriers
Y Gao, XL Liu, XR Li - International journal of nanomedicine, 2011 - Taylor & Francis
RNA interference is a powerful method for the knockdown of pathologically relevant genes.
Small interfering RNAs (siRNAs) have been widely demonstrated as effective biomedical …
Small interfering RNAs (siRNAs) have been widely demonstrated as effective biomedical …
[HTML][HTML] Nanoscale delivery systems for microRNAs in cancer therapy
S Boca, D Gulei, AA Zimta, A Onaciu, L Magdo… - Cellular and Molecular …, 2020 - Springer
Concomitant with advances in research regarding the role of miRNAs in sustaining
carcinogenesis, major concerns about their delivery options for anticancer therapies have …
carcinogenesis, major concerns about their delivery options for anticancer therapies have …
[HTML][HTML] Delivery systems for siRNA drug development in cancer therapy
C Xu, J Wang - Asian Journal of Pharmaceutical Sciences, 2015 - Elsevier
Since the discovery of the Nobel prize-winning mechanism of RNA interference (RNAi) ten
years ago, it has become a promising drug target for the treatment of multiple diseases …
years ago, it has become a promising drug target for the treatment of multiple diseases …
siRNA delivery strategies: a comprehensive review of recent developments
siRNA is a promising therapeutic solution to address gene overexpression or mutations as a
post-transcriptional gene regulation process for several pathological conditions such as viral …
post-transcriptional gene regulation process for several pathological conditions such as viral …
Nanovector delivery of siRNA for cancer therapy
RNA interference holds the promise to knock down expression of every cancer gene. Both
academic laboratories and pharmaceutical companies have committed heavily on …
academic laboratories and pharmaceutical companies have committed heavily on …
Small interfering RNAs (siRNAs) in cancer therapy: a nano-based approach
G Mahmoodi Chalbatani, H Dana… - International journal …, 2019 - Taylor & Francis
Cancer is one of the most complex diseases that has resulted in multiple genetic disorders
and cellular abnormalities. Globally, cancer is the most common health concern disease that …
and cellular abnormalities. Globally, cancer is the most common health concern disease that …
Small interfering RNA therapy in cancer: mechanism, potential targets, and clinical applications
Background: Small interfering RNA (siRNA) has become a powerful tool in knocking down
or silencing gene expression in most cells. siRNA-based therapy has shown great promise …
or silencing gene expression in most cells. siRNA-based therapy has shown great promise …
A review of the current status of siRNA nanomedicines in the treatment of cancer
P Resnier, T Montier, V Mathieu, JP Benoit, C Passirani - Biomaterials, 2013 - Elsevier
RNA interference currently offers new opportunities for gene therapy by the specific
extinction of targeted gene (s) in cancer diseases. However, the main challenge for nucleic …
extinction of targeted gene (s) in cancer diseases. However, the main challenge for nucleic …
[HTML][HTML] Small interfering RNA for cancer treatment: overcoming hurdles in delivery
In many ways, cancer cells are different from healthy cells. A lot of tactical nano-based drug
delivery systems are based on the difference between cancer and healthy cells. Currently …
delivery systems are based on the difference between cancer and healthy cells. Currently …