Time to transition from a negative nomenclature describing what NAFLD is not, to a novel, pathophysiology-based, umbrella classification of fatty liver disease (FLD)

L Valenzuela-Vallejo, CS Mantzoros - Metabolism, 2022 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) is a definition of a prevalent condition that has
been given a name describing what the disease is not, mainly due to gaps in the …

Making progress in nonalcoholic fatty liver disease (NAFLD) as we are transitioning from the era of NAFLD to dys-metabolism associated fatty liver disease (DAFLD)

SA Polyzos, CS Mantzoros - Metabolism, 2020 - Elsevier
This supplement to “Metabolism, Clinical and Experimental” is dedicated to nonalcoholic
fatty liver disease (NAFLD), a disease closely linked with the insulin resistance (IR) …

Past, present and future perspectives in nonalcoholic fatty liver disease

AJ Sanyal - Nature reviews Gastroenterology & hepatology, 2019 - nature.com
Nonalcoholic fatty liver disease (NAFLD) was first described as a distinct clinical entity four
decades ago. However, the condition has become the centre of attention within hepatology …

[HTML][HTML] Recent advances in NAFLD: current areas of contention

E Jennison, CD Byrne - Faculty reviews, 2023 - ncbi.nlm.nih.gov
This brief review focuses on two contentious issues within the field of non-alcoholic fatty liver
disease (NAFLD); the first is the recent effort to redefine NAFLD as metabolic (dysfunction) …

From non-alcoholic fatty liver disease (NAFLD) to steatotic liver disease (SLD): an ongoing journey towards refining the terminology for this prevalent metabolic …

M Kokkorakis, C Boutari, N Katsiki… - Metabolism-Clinical …, 2023 - metabolismjournal.com
Non-alcoholic fatty liver disease (NAFLD) is a prevalent metabolic condition closely
associated with genetic predisposition and/or obesity, lipodystrophy, and insulin resistance …

From NAFLD to MASLD: updated naming and diagnosis criteria for fatty liver disease

ME Rinella, S Sookoian - Journal of Lipid Research, 2024 - ASBMB
Metabolic dysfunction-associated steatotic liver disease (MASLD), formerly known as
nonalcoholic fatty liver disease (NAFLD), is a prevalent chronic liver disease worldwide …

[HTML][HTML] MAFLD: How is it different from NAFLD?

C Gofton, Y Upendran, MH Zheng… - Clinical and molecular …, 2023 - ncbi.nlm.nih.gov
Abstract “Metabolic dysfunction-associated fatty liver disease (MAFLD)” is the term
suggested in 2020 to refer to fatty liver disease related to systemic metabolic dysregulation …

From NAFLD to MAFLD: implications of a premature change in terminology

ZM Younossi, ME Rinella, AJ Sanyal, SA Harrison… - …, 2021 - Wiley Online Library
Despite the substantial gains in our understanding of NAFLD/NASH over the past 2
decades, there has been some dissatisfaction with the terminology “non‐alcoholic” which …

[HTML][HTML] Heterogeneity of non-alcoholic fatty liver disease: Implications for clinical practice and research activity

P Pal, R Palui, S Ray - World Journal of Hepatology, 2021 - ncbi.nlm.nih.gov
Non-alcoholic fatty liver disease (NAFLD) is a heterogeneous condition with a wide
spectrum of clinical presentations and natural history and disease severity. There is also …

MAFLD: a consensus-driven proposed nomenclature for metabolic associated fatty liver disease

M Eslam, AJ Sanyal, J George, A Sanyal… - Gastroenterology, 2020 - Elsevier
Fatty liver associated with metabolic dysfunction is common, affects a quarter of the
population, and has no approved drug therapy. Although pharmacotherapies are in …