Critical evaluation of equations for serum osmolality: Proposals for effective clinical utility

EO Ebonwu, SE Nagel, L Repsold, TS Pillay - Clinica Chimica Acta, 2020 - Elsevier
Background Many studies have assessed the predictive accuracy of serum osmolality
equations. Different approaches for selecting a usable equation were compared using thirty …

Derivation and validation of a new formula for plasma osmolality estimation

JL Martín-Calderón, LR Tuesta-Reina - Clinical Biochemistry, 2022 - Elsevier
Background Plasma osmolality is a physic and chemical property of interest in emergency
medicine. This magnitude can be measured at the laboratory, but it is usually estimated with …

Choice of the best equation for plasma osmolality calculation: comparison of fourteen formulae

JL Martín-Calderón, F Bustos, LR Tuesta-Reina… - Clinical …, 2015 - Elsevier
Background Many different equations have been previously described to estimate plasma
osmolality. The aim of this study is to compare 14 of these equations, in order to determine …

The osmolal gap: what has changed?

JDE Whittington, SL La'ulu, JJH Hunsaker… - Clinical …, 2010 - academic.oup.com
The osmolal gap (OG) 1 is calculated in the emergency department (ED) when ingestion of
ethylene glycol, methanol, isopropyl alcohol, acetone, or other osmotically active substances …

Comparison of methods for calculating serum osmolality: multivariate linear regression analysis

M Rasouli, KR Kalantari - Clinical Chemistry and Laboratory …, 2005 - degruyter.com
Background: There are several methods for calculating serum osmolality, and their
accordance with measured osmolality is the subject of controversy. Methods: The …

[HTML][HTML] Validation of equations used to predict plasma osmolality in a healthy adult cohort

KR Heavens, RW Kenefick, EM Caruso… - The American journal of …, 2014 - Elsevier
Background: Plasma osmometry and the osmol gap have long been used to provide
clinicians with important diagnostic and prognostic patient information. Objective: We …

[HTML][HTML] Harmonisation of osmolal gap–can we use a common formula?

KW Choy, N Wijeratne, ZX Lu… - The Clinical Biochemist …, 2016 - ncbi.nlm.nih.gov
Osmolal gap is the difference between the measured osmolality and a calculated osmolality
based on the major commonly measured osmotically active particles. The perceived gap …

Method-specific reference intervals for serum anion gap and osmolality

WL Roberts, WD Paulson - Clinical chemistry, 1998 - academic.oup.com
We wish to comment on reference intervals for the serum anion gap and osmolality. The
serum anion gap, which is most commonly defined as AG Na-Cl-TCO2, traditionally has had …

Comparison of measured and calculated osmolality levels

E Kar, E Kocatürk, Z Küskü Kiraz, B Demiryürek… - Clinical and …, 2020 - Springer
Background Serum osmolality levels are measured to determine acid–base and electrolyte
imbalance in serum. In cases where measurement is not possible, the serum osmolality …

[HTML][HTML] The measurement of serum osmolality and its application to clinical practice and laboratory: literature review

DK Faria, ME Mendes, NM Sumita - Jornal Brasileiro de Patologia e …, 2017 - SciELO Brasil
Introduction: Serum osmolality is an essential laboratory parameter to understand several
clinical disorders such as electrolyte disturbances, exogenous intoxication and hydration …