Muscle–Brain crosstalk in cognitive impairment

X Han, M Ashraf, SM Tipparaju, W Xuan - Frontiers in Aging …, 2023 - frontiersin.org
Sarcopenia is an age-related, involuntary loss of skeletal muscle mass and strength.
Alzheimer's disease (AD) is the most common cause of dementia in elderly adults. To date …

Sarcopenia and Cognitive decline in older adults: targeting the muscle–brain Axis

B Arosio, R Calvani, E Ferri, HJ Coelho-Junior… - Nutrients, 2023 - mdpi.com
Declines in physical performance and cognition are commonly observed in older adults. The
geroscience paradigm posits that a set of processes and pathways shared among age …

Sarcopenia and cognitive function: role of myokines in muscle brain cross-talk

L Scisciola, RA Fontanella, Surina, V Cataldo… - Life, 2021 - mdpi.com
Sarcopenia is a geriatric syndrome characterized by the progressive degeneration of muscle
mass and function, and it is associated with severe complications, which are falls, functional …

Skeletal muscle health and cognitive function: a narrative review

SX Sui, LJ Williams, KL Holloway-Kew… - International journal of …, 2020 - mdpi.com
Sarcopenia is the loss of skeletal muscle mass and function with advancing age. It involves
both complex genetic and modifiable risk factors, such as lack of exercise, malnutrition and …

[HTML][HTML] Does the regulation of skeletal muscle influence cognitive function? A scoping review of pre-clinical evidence

C Liu, PY Wong, SKH Chow, WH Cheung… - Journal of Orthopaedic …, 2023 - Elsevier
Background Cognitive impairment is a major challenge for elderlies, as it can progress in a
rapid manner and effective treatments are limited. Sarcopenic elderlies have a higher risk of …

Are sarcopenia and cognitive dysfunction comorbid after stroke in the context of brain–muscle crosstalk?

SX Sui, B Hordacre, JA Pasco - Biomedicines, 2021 - mdpi.com
Stroke is a leading cause of death and disability and is responsible for a significant
economic burden. Sarcopenia and cognitive dysfunction are common consequences of …

[HTML][HTML] A new paradigm in sarcopenia: Cognitive impairment caused by imbalanced myokine secretion and vascular dysfunction

D Jo, G Yoon, OY Kim, J Song - Biomedicine & Pharmacotherapy, 2022 - Elsevier
Sarcopenia characterized by reduced skeletal muscle mass and decreased muscle strength
is increasing in prevalence globally. The pathophysiology of sarcopenia is related to various …

Sarcopenia and the common mental disorders: a potential regulatory role of skeletal muscle on brain function?

JA Pasco, LJ Williams, FN Jacka, N Stupka… - Current osteoporosis …, 2015 - Springer
While it is understood that body composition impacts on physical conditions, such as
diabetes and cardiovascular disease, it is only now apparent that body composition might …

Sarcopenia and neuroscience: learning to communicate

BC Clark, RG Carson - The Journals of Gerontology: Series A, 2021 - academic.oup.com
In the 1990s and early 2000s, the common definition for sarcopenia was age-related loss of
skeletal muscle, and low levels of muscle mass were central to sarcopenia diagnosis. In …

Pathophysiological mechanisms of sarcopenia in aging and in muscular dystrophy: a translational approach

L Merlini, P Bonaldo, E Marzetti - Frontiers in aging neuroscience, 2015 - frontiersin.org
Sarcopenia and muscular dystrophy are both characterized by the loss of muscle mass and
increased intramuscular fibrosis. The two conditions also share several pathophysiological …