Selective transmission of multidrug resistant HIV to a newborn related to poor maternal adherence

N Desai, M Mathur - Sexually transmitted infections, 2003 - sti.bmj.com
Objectives: To report perinatal transmission of multidrug resistant (MDR) HIV related to
variable maternal adherence antenatally. Methods: Case study including review of clinic …

Zidovudine with nevirapine for the prevention of HIV mother‐to‐child transmission reduces nevirapine resistance in mothers from the Western Cape, South Africa

GU Van Zyl, M Claassen, S Engelbrecht… - Journal of medical …, 2008 - Wiley Online Library
Abstract In the Western Cape province of South Africa, an intensified regimen for the
prevention‐of‐mother‐to‐child‐transmission‐of‐HIV consisting of zidovudine (AZT) from 34 …

Prevention of mother-to-child transmission of HIV: antiretroviral strategies

JS Read - Clinics in perinatology, 2010 - perinatology.theclinics.com
guidelines. Specifically, the review focuses on antiretrovirals for the secondary prevention of
HIV-1 infection--prevention of HIV-1 transmission from a pregnant HIV-1–infected woman to …

Treating HIV during pregnancy: an update on safety issues

DH Watts - Drug Safety, 2006 - Springer
The expanded use of multiple antiretroviral drugs during pregnancy has led to a reduction in
the occurrence of perinatal transmission of HIV to< 2%, but has led to concerns regarding …

The role of antiretrovirals and drug resistance in vertical transmission of HIV‐1 infection

BG Brenner, MA Wainberg - Annals of the New York Academy …, 2000 - Wiley Online Library
Large‐cohort studies in North America, Europe, and Thailand have shown that zidovudine/
azidothymidine (AZT) monotherapy, given at the late stages of pregnancy, is of proven …

Single‐dose nevirapine and drug resistance: the more you look, the more you find

SM Hammer - The Journal of Infectious Diseases, 2005 - academic.oup.com
Within the context of the historic development of drugs to treat HIV infection, there is perhaps
no subject that has created more controversy than the use of these agents to interrupt the …

Prevalence of drug-resistance mutations and non-subtype B strains among HIV-infected infants from New York State

M Karchava, W Pulver, L Smith, S Philpott… - JAIDS Journal of …, 2006 - journals.lww.com
Prevalence studies indicate that transmission of drug-resistant HIV has been rising in the
adult population, but data from the perinatally infected pediatric population are limited. In this …

From research to implementation: challenges in the prevention of mother to child HIV transmission in the developing world

LA Guay - Trends in Molecular Medicine, 2001 - cell.com
Scientific research has identified anti-retroviral regimens effective in the prevention of
mother to child HIV transmission. Yet, 1800 HIV-infected infants are born every day. The …

Maternal single-dose nevirapine versus placebo as part of an antiretroviral strategy to prevent mother-to-child HIV transmission in Botswana

RL Shapiro, I Thior, PB Gilbert, S Lockman, C Wester… - Aids, 2006 - journals.lww.com
Background: Single-dose nevirapine given to women and infants reduces mother-to-child
HIV transmission, but nevirapine resistance develops in a large percentage of women …

HIV drug resistance in infants increases with changing prevention of mother-to-child transmission regimens

LK Poppe, C Chunda-Liyoka, EH Kwon, C Gondwe… - Aids, 2017 - journals.lww.com
Objectives: The objectives of this study were to determine HIV drug resistance (HIVDR)
prevalence in Zambian infants upon diagnosis, and to determine how changing prevention …