Potential natural biomolecules targeting JAK/STAT/SOCS signaling in the management of atopic dermatitis
SR Kopalli, VP Annamneedi, S Koppula - Molecules, 2022 - mdpi.com
Atopic dermatitis (AD) is a chronic inflammatory skin disease caused by the dysregulation of
cytokines and other immune mediators. JAK/STAT is a classical signal transduction pathway …
cytokines and other immune mediators. JAK/STAT is a classical signal transduction pathway …
JAK–STAT signaling pathway in the pathogenesis of atopic dermatitis: An updated review
Atopic dermatitis (AD) is a chronic, inflammatory, pruritic form of dermatosis with
heterogeneous manifestations that can substantially affect patients' quality of life. AD has a …
heterogeneous manifestations that can substantially affect patients' quality of life. AD has a …
The involvement of the JAK-STAT signaling pathway in chronic inflammatory skin disease atopic dermatitis
L Bao, H Zhang, LS Chan - Jak-Stat, 2013 - Taylor & Francis
Atopic dermatitis (AD), a common chronic inflammatory skin disease, is characterized by
inflammatory cell skin infiltration. The JAK-STAT pathway has been shown to play an …
inflammatory cell skin infiltration. The JAK-STAT pathway has been shown to play an …
The JAK/STAT pathway and its selective inhibition in the treatment of atopic dermatitis: a systematic review
A Tsiogka, M Kyriazopoulou… - Journal of Clinical …, 2022 - mdpi.com
In recent years, the broadening understanding of the pathogenesis of atopic dermatitis (AD)
has led to the development of novel therapeutic molecules, that target core inflammatory …
has led to the development of novel therapeutic molecules, that target core inflammatory …
Innovation in the treatment of atopic dermatitis: emerging topical and oral Janus kinase inhibitors
C Nakashima, S Yanagihara, A Otsuka - Allergology International, 2022 - jstage.jst.go.jp
abstract Atopic dermatitis (AD) is characterized by chronic, eczematous, severe pruritic skin
lesions. The knowledge on the pathogenesis of AD is driving the development of new drugs …
lesions. The knowledge on the pathogenesis of AD is driving the development of new drugs …
Aberrant expression of suppressor of cytokine signaling (SOCS) molecules contributes to the development of allergic diseases
A Jafarzadeh, P Chauhan, M Nemati… - Clinical & …, 2023 - Wiley Online Library
Suppressor of cytokine signalling (SOCS) proteins bind to certain cytokine receptors, Janus
kinases and signalling molecules to regulate signalling pathways, thus controlling immune …
kinases and signalling molecules to regulate signalling pathways, thus controlling immune …
Novel therapeutic targets for the treatment of atopic dermatitis
G Tsuji, K Yamamura, K Kawamura, M Kido-Nakahara… - Biomedicines, 2023 - mdpi.com
Atopic dermatitis (AD) is a chronic inflammatory skin disease that significantly impacts
quality of life. The pathogenesis of AD is a complex combination of skin barrier dysfunction …
quality of life. The pathogenesis of AD is a complex combination of skin barrier dysfunction …
The role of Janus kinase signaling in the pathology of atopic dermatitis
Atopic dermatitis (AD) is a heterogeneous, chronic, relapsing, inflammatory skin disease
associated with considerable physical, psychological, and economic burden. Pathology of …
associated with considerable physical, psychological, and economic burden. Pathology of …
A new horizon for atopic dermatitis treatments: JAK inhibitors
M Tampa, CI Mitran, MI Mitran… - Journal of Personalized …, 2023 - mdpi.com
The article entitled “Application of Janus Kinase Inhibitors in Atopic Dermatitis: An Updated
Systematic Review and Meta-Analysis of Clinical Trials” that belongs to the Special …
Systematic Review and Meta-Analysis of Clinical Trials” that belongs to the Special …
Inflammatory Skin Diseases: Focus on the Role of Suppressors of Cytokine Signaling (SOCS) Proteins
Inflammatory skin diseases include a series of disorders characterized by a strong activation
of the innate and adaptive immune system in which proinflammatory cytokines play a …
of the innate and adaptive immune system in which proinflammatory cytokines play a …