Bacterial diversity of diabetic foot ulcers: current status and future prospectives

F Sadeghpour Heravi, M Zakrzewski, K Vickery… - Journal of clinical …, 2019 - mdpi.com
Diabetic foot ulcers (DFUs) and diabetic foot infections (DFIs) are associated with reduced
patient quality of life, lower-extremity amputation, hospitalization, and high morbidity and …

Next generation DNA sequencing of tissues from infected diabetic foot ulcers

M Malone, K Johani, SO Jensen, IB Gosbell… - …, 2017 - thelancet.com
We used next generation DNA sequencing to profile the microbiome of infected Diabetic
Foot Ulcers (DFUs). The microbiota was correlated to clinical parameters and treatment …

[HTML][HTML] Diabetic foot ulcer microbiome: one small step for molecular microbiology... One giant leap for understanding diabetic foot ulcers?

BA Lipsky, JL Richard, JP Lavigne - Diabetes, 2013 - ncbi.nlm.nih.gov
Foot infections in individuals with diabetes are a major cause of morbidity, constituting the
most common reason for both diabetes-related hospitalization and lower extremity …

The dynamic wound microbiome

C Liu, AJ Ponsero, DG Armstrong, BA Lipsky… - BMC medicine, 2020 - Springer
Abstract Background Diabetic foot ulcers (DFUs) account for the majority of all limb
amputations and hospitalizations due to diabetes complications. With 30 million cases of …

Microbial community distribution and core microbiome in successive wound grades of individuals with diabetic foot ulcers

A Jnana, V Muthuraman, VK Varghese… - Applied and …, 2020 - Am Soc Microbiol
Diabetic foot ulcer (DFU) is a major complication of diabetes with high morbidity and
mortality rates. The pathogenesis of DFUs is governed by a complex milieu of environmental …

The neuropathic diabetic foot ulcer microbiome is associated with clinical factors

SE Gardner, SL Hillis, K Heilmann, JA Segre… - Diabetes, 2013 - Am Diabetes Assoc
Nonhealing diabetic foot ulcers (DFUs) are a common and costly complication of diabetes.
Microbial burden, or “bioburden,” is believed to underlie delayed healing, although little is …

The microbiome of diabetic foot ulcers: a comparison of swab and tissue biopsy wound sampling techniques using 16S rRNA gene sequencing

J Travis, M Malone, H Hu, A Baten, K Johani… - BMC microbiology, 2020 - Springer
Background Health-care professionals need to collect wound samples to identify potential
pathogens that contribute to wound infection. Obtaining appropriate samples from diabetic …

Classification, microbiology and treatment of diabetic foot infections

R Ghotaslou, MY Memar, N Alizadeh - Journal of wound care, 2018 - magonlinelibrary.com
Diabetic foot ulcers (DFUs) are a common complication of type-1 and type-2 diabetes. About
10–15% of patients with diabetes develop foot ulcers. A validated foot ulcer classification …

One step closer to understanding the role of bacteria in diabetic foot ulcers: characterising the microbiome of ulcers

K Smith, A Collier, EM Townsend, LE O'Donnell… - BMC microbiology, 2016 - Springer
Background The aim of this study was to characterise the microbiome of new and recurrent
diabetic foot ulcers using 16S amplicon sequencing (16S AS), allowing the identification of a …

[HTML][HTML] The diabetic foot microbiota: A review

J Jneid, JP Lavigne, B La Scola, N Cassir - Human Microbiome Journal, 2017 - Elsevier
Diabetes mellitus represents a major public health threat worldwide. A serious complication
of diabetes is the development of foot ulcers which, when they become infected, are the …