Periosteum, bone's “smart” bounding membrane, exhibits direction‐dependent permeability

SF Evans, JB Parent, CE Lasko, X Zhen… - Journal of Bone and …, 2013 - academic.oup.com
The periosteum serves as bone's bounding membrane, exhibits hallmarks of
semipermeable epithelial barrier membranes, and contains mechanically sensitive …

Elucidating multiscale periosteal mechanobiology: a key to unlocking the smart properties and regenerative capacity of the periosteum?

SF Evans, H Chang, ML Knothe Tate - Tissue Engineering Part B …, 2013 - liebertpub.com
The periosteum, a thin, fibrous tissue layer covering most bones, resides in a dynamic,
mechanically loaded environment. The periosteum also provides a niche for mesenchymal …

[HTML][HTML] Periosteum mechanobiology and mechanistic insights for regenerative medicine

MLK Tate, YC Nicole, I Jalilian, AF Pereira… - BoneKEy …, 2016 - ncbi.nlm.nih.gov
Periosteum is a smart mechanobiological material that serves as a habitat and delivery
vehicle for stem cells as well as biological factors that modulate tissue genesis and healing …

Current insights on the regenerative potential of the periosteum: molecular, cellular, and endogenous engineering approaches

C Colnot, X Zhang, MLK Tate - Journal of Orthopaedic …, 2012 - Wiley Online Library
While century old clinical reports document the periosteum's remarkable regenerative
capacity, only in the past decade have scientists undertaken mechanistic investigations of its …

Periosteum: biology, regulation, and response to osteoporosis therapies

MR Allen, JM Hock, DB Burr - Bone, 2004 - Elsevier
Periosteum contains osteogenic cells that regulate the outer shape of bone and work in
coordination with inner cortical endosteum to regulate cortical thickness and the size and …

The periosteal microcirculation in health and disease: an update on clinical significance

A Szabó, Á Janovszky, L Pócs, M Boros - Microvascular research, 2017 - Elsevier
Apart from its nutritive functions, the periosteum critically affects bone regeneration via its
stem/osteoprogenitor cell content. Normal healing after bone fractures, trauma–orthopedic …

Toward an expanded understanding of the role of the periosteum in skeletal health

ES Orwoll - Journal of Bone and Mineral Research, 2003 - academic.oup.com
THE RECOGNITION THAT bone size is an important deter-minant of bone strength has led
inexorably to a consideration of factors that affect periosteal events. Similarly, there has …

Live tissue imaging to elucidate mechanical modulation of stem cell niche quiescence

NYC Yu, CA O'Brien, I Slapetova… - Stem cells …, 2017 - academic.oup.com
The periosteum, a composite cellular connective tissue, bounds all nonarticular bone
surfaces. Like Velcro, collagenous Sharpey's fibers anchor the periosteum in a prestressed …

Imaging and quantifying solute transport across periosteum: implications for muscle–bone crosstalk

X Lai, C Price, XL Lu, L Wang - Bone, 2014 - Elsevier
Muscle and bone are known to act as a functional unit and communicate biochemically
during tissue development and maintenance. Muscle-derived factors (myokines) have been …

A periosteum-derived cell line to study the role of BMP/TGFβ signaling in periosteal cell behavior and function

ER Moore, DE Maridas, L Gamer, G Chen… - Frontiers in …, 2023 - frontiersin.org
The periosteum is a thin tissue surrounding each skeletal element that contains stem and
progenitor cells involved in bone development, postnatal appositional bone growth, load …