Eupalinolide J induces apoptosis, cell cycle arrest, mitochondrial membrane potential disruption and DNA damage in human prostate cancer cells
Z Wu, X Xu, L Dai, Y Wang, B Yang… - The Journal of …, 2020 - jstage.jst.go.jp
Eupalinolide J (EJ) is a new sesquiterpene lactone isolated from Eupatorium lindleyanum
DC. In the present study, we investigated the anti-cancer activity of EJ on cell proliferation in …
DC. In the present study, we investigated the anti-cancer activity of EJ on cell proliferation in …
[HTML][HTML] Eupalinolide O, a novel sesquiterpene lactone from Eupatorium lindleyanum DC., induces cell cycle arrest and apoptosis in human MDA-MB-468 breast …
B Yang, Y Zhao, C Lou, H Zhao - Oncology Reports, 2016 - spandidos-publications.com
Sesquiterpene lactones have been confirmed to have potential antitumor activity. Here, we
demonstrated that Eupalinolide O (EO), a novel sesquiterpene lactone isolated from …
demonstrated that Eupalinolide O (EO), a novel sesquiterpene lactone isolated from …
Eupalinolide A induces autophagy via the ROS/ERK signaling pathway in hepatocellular carcinoma cells in vitro and in vivo
Y Zhang, F Dong, Z Cao, T Wang… - International …, 2022 - spandidos-publications.com
Hepatocellular carcinoma is the most common primary malignancy of the liver. The current
systemic drugs used to treat hepatocellular carcinoma result in low overall survival time. It …
systemic drugs used to treat hepatocellular carcinoma result in low overall survival time. It …
New 6(17)-epoxylathyrane diterpene: aellinane from Euphorbia aellenii induces apoptosis via mitochondrial pathway in ovarian cancer cell line
Euphorbia species have been used in traditional medicine in many countries for the
treatment of cancer. This article aims to evaluate the capability of a new lathyrane diterpene …
treatment of cancer. This article aims to evaluate the capability of a new lathyrane diterpene …
Eupalinolide O Induces Apoptosis in Human Triple‐Negative Breast Cancer Cells via Modulating ROS Generation and Akt/p38 MAPK Signaling Pathway
Y Zhao, L Fu, J Chen, J Zhou, C Tian… - Journal of …, 2022 - Wiley Online Library
Background. Triple‐negative breast cancer (TNBC) is a subtype of breast cancer with limited
therapeutic options. Eupalinolide O (EO) was reported to inhibit tumor growth. This study is …
therapeutic options. Eupalinolide O (EO) was reported to inhibit tumor growth. This study is …
Eupalinolide J Suppresses the Growth of Triple-Negative Breast Cancer Cells via Targeting STAT3 Signaling Pathway
C Lou, Y Chen, J Zhang, B Yang, H Zhao - Frontiers in Pharmacology, 2019 - frontiersin.org
Persistent activation of STAT3 plays an important role in the development of triple-negative
breast cancer (TNBC), and suppression of STAT3 is considered as a novel approach for …
breast cancer (TNBC), and suppression of STAT3 is considered as a novel approach for …
[HTML][HTML] Persianolide-A, an eudesmanolide-type sesquiterpene lactone from Artemisia kopetdaghensis, induces apoptosis by regulating ERK signaling pathways
SM Ebrahimi, J Asadi, M Fattahian… - Research in …, 2024 - journals.lww.com
Background and purpose: Herbal components, particularly sesquiterpenes, are
progressively recognized as a crucial resource for developing effective therapeutic agents …
progressively recognized as a crucial resource for developing effective therapeutic agents …
[HTML][HTML] Eupalinolide B inhibits hepatic carcinoma by inducing ferroptosis and ROS-ER-JNK pathway: Inhibition of Eupalinolide B in hepatic carcinoma
Y Zhang, H Zhang, J Mu, M Han, Z Cao… - Acta Biochimica et …, 2022 - ncbi.nlm.nih.gov
Primary hepatic carcinoma is a common malignant tumor. The classic molecular targeted
drug sorafenib is costly and is only effective for some patients. Therefore, it is of great clinical …
drug sorafenib is costly and is only effective for some patients. Therefore, it is of great clinical …
Eupalinolide J Inhibits Cancer Metastasis by Promoting STAT3 Ubiquitin-Dependent Degradation
H Hu, H Bai, L Huang, B Yang, H Zhao - Molecules, 2023 - mdpi.com
Eupalinolide J (EJ) is an active component from Eupatorium lindleyanum DC.(EL), which
was reported to have good antitumor activity via STAT3 and Akt signaling pathways. In this …
was reported to have good antitumor activity via STAT3 and Akt signaling pathways. In this …
Eupalitin induces apoptosis in prostate carcinoma cells through ROS generation and increase of caspase‐3 activity
Prostate cancer is the second most common malignancy in the human reproductive system.
Eupalitin is one of the O‐methylated flavonol‐exhibited enhanced cancer chemopreventive …
Eupalitin is one of the O‐methylated flavonol‐exhibited enhanced cancer chemopreventive …