Eupalinolide J (EJ) is a new sesquiterpene lactone isolated from Eupatorium lindleyanum
DC. In the present study, we investigated the anti-cancer activity of EJ on cell proliferation in …

Sesquiterpene lactones have been confirmed to have potential antitumor activity. Here, we
demonstrated that Eupalinolide O (EO), a novel sesquiterpene lactone isolated from …

Hepatocellular carcinoma is the most common primary malignancy of the liver. The current
systemic drugs used to treat hepatocellular carcinoma result in low overall survival time. It …

Euphorbia species have been used in traditional medicine in many countries for the
treatment of cancer. This article aims to evaluate the capability of a new lathyrane diterpene …

Background. Triple‐negative breast cancer (TNBC) is a subtype of breast cancer with limited
therapeutic options. Eupalinolide O (EO) was reported to inhibit tumor growth. This study is …

Persistent activation of STAT3 plays an important role in the development of triple-negative
breast cancer (TNBC), and suppression of STAT3 is considered as a novel approach for …

Background and purpose: Herbal components, particularly sesquiterpenes, are
progressively recognized as a crucial resource for developing effective therapeutic agents …

Primary hepatic carcinoma is a common malignant tumor. The classic molecular targeted
drug sorafenib is costly and is only effective for some patients. Therefore, it is of great clinical …

Eupalinolide J (EJ) is an active component from Eupatorium lindleyanum DC.(EL), which
was reported to have good antitumor activity via STAT3 and Akt signaling pathways. In this …

Prostate cancer is the second most common malignancy in the human reproductive system.
Eupalitin is one of the O‐methylated flavonol‐exhibited enhanced cancer chemopreventive …