PAH-CALUX, an optimized bioassay for AhR-mediated hazard identification of polycyclic aromatic hydrocarbons (PAHs) as individual compounds and in complex …
B Pieterse, E Felzel, R Winter… - … science & technology, 2013 - ACS Publications
Polycyclic aromatic hydrocarbons (PAHs) represent a class of ubiquitously occurring
environmental compounds that are implicated in a wide range of toxicological effects …
environmental compounds that are implicated in a wide range of toxicological effects …
Complex mixture toxicity for single and multiple species: proposed methodologies
D De Zwart, L Posthuma - Environmental Toxicology and …, 2005 - Wiley Online Library
Methods for the assessment of ecological risks associated with exposure to defined mixtures
of toxicants are reviewed and formalized for single‐species toxicity. Depending on the …
of toxicants are reviewed and formalized for single‐species toxicity. Depending on the …
Development of an in Vitro-Based Risk Assessment Framework for Predicting Ambient Particulate Matter-Bound Polycyclic Aromatic Hydrocarbon-Activated Toxicity …
Polycyclic aromatic hydrocarbons (PAHs) are widely distributed throughout the atmosphere
as mixtures attached to ambient particulate matter (PM). PAHs usually elicit similar …
as mixtures attached to ambient particulate matter (PM). PAHs usually elicit similar …
Binary Mixtures of Polycyclic Aromatic Hydrocarbons Display Nonadditive Mixture Interactions in an In Vitro Liver Cell Model
SJ Gaskill, ED Bruce - Risk Analysis, 2016 - Wiley Online Library
Polycyclic aromatic hydrocarbons (PAHs) have been labeled contaminants of concern due
to their carcinogenic potential, insufficient toxicological data, environmental ubiquity, and …
to their carcinogenic potential, insufficient toxicological data, environmental ubiquity, and …
Sensitivity of different endpoints for in vitro measurement of genotoxicity of extractable organic matter associated with ambient airborne particles (PM10)
A Gábelová, Z Valovičová, G Bačová, J Lábaj… - Mutation Research …, 2007 - Elsevier
Sensitivity and correlations among three endpoints were evaluated to assess the genotoxic
potential of organic complex mixtures in vitro. This study was focused on DNA adduct …
potential of organic complex mixtures in vitro. This study was focused on DNA adduct …
Bioanalytical equivalents and relative potencies for predicting the biological effects of mixtures
Bioanalytical equivalents (BEQs) of mixtures and environmental samples are widely used to
reflect the potential threat of pollutants in the environment and can be obtained by bioassays …
reflect the potential threat of pollutants in the environment and can be obtained by bioassays …
Mechanism-based classification of PAH mixtures to predict carcinogenic potential
SC Tilton, LK Siddens, SK Krueger… - Toxicological …, 2015 - academic.oup.com
We have previously shown that relative potency factors and DNA adduct measurements are
inadequate for predicting carcinogenicity of certain polycyclic aromatic hydrocarbons (PAHs) …
inadequate for predicting carcinogenicity of certain polycyclic aromatic hydrocarbons (PAHs) …
Toxic organic substances and marker compounds in size-segregated urban particulate matter-Implications for involvement in the in vitro bioactivity of the extractable …
Toxic organic substances and polar organic marker compounds, ie polychlorinated
biphenyls (PCBs), organochlorine pesticides (OCPs), polybrominated diphenyl ethers …
biphenyls (PCBs), organochlorine pesticides (OCPs), polybrominated diphenyl ethers …
[PDF][PDF] Monitoring and risk analysis of PAHs in the environment
Polycyclic aromatic hydrocarbons (PAHs) are a unique class of organic pollutants containing
two or more fused aromatic rings, which are toxic and potential carcinogens. They are …
two or more fused aromatic rings, which are toxic and potential carcinogens. They are …
A look beyond the priority: A systematic review of the genotoxic, mutagenic, and carcinogenic endpoints of non-priority PAHs
FC da Silva Junior, MBMC Felipe, DEF de Castro… - Environmental …, 2021 - Elsevier
Abstract Knowledge of the toxic potential of polycyclic aromatic hydrocarbons (PAHs) has
increased over time. Much of this knowledge is about the 16 United States-Environmental …
increased over time. Much of this knowledge is about the 16 United States-Environmental …