The assumption of additivity applied in the risk assessment of environmental mixtures
containing carcinogenic polycyclic aromatic hydrocarbons (PAHs) was investigated using …

A substantial effort has been spent over the past few decades to label toxicologic interaction
outcomes as synergistic, antagonistic, or additive. Although useful in influencing the …

Although particulate matter (PM) is composed of various chemicals, investigations regarding
the toxicity that results from mixing the substances in PM are insufficient. In this study, the …

In this study, organic extracts of total suspended particles (TSP) and the particulate matter
(PM) with the size below 2.5 μm (PM2. 5) combined with organic extracts of the gas phase …

Abstract Background The EU Council and Parliament recently agreed on a new regulation
that will implement a new EU-wide, harmonized system for the authorization for biocidal …

Traditionally, contamination of air has been evaluated primarily by chemical analyses of
indicator contaminants and these studies have focused mainly on compounds associated …

Abstract Polycyclic Aromatic Hydrocarbons (PAHs) form a family of compounds that are
generally found in complex mixtures. PAHs can lead to the development of carcinogenesis …

Urban aerosol samples collected in Barcelona between 2008 and 2009 were toxicologically
characterised by means of two complementary methodologies allowing evaluation of their …

There is a growing need to establish alternative approaches for mixture safety assessment
of polycyclic aromatic hydrocarbons (PAHs). Due to limitations with current component …

In the United States, several proposed approaches for using bioassays for the risk
assessment of complex hazardous mixtures require that selected mixtures be “sufficiently …