In vitro genotoxicity of PAH mixtures and organic extract from urban air particles: Part I: Acellular assay

B Binkova, J Topinka, RJ Sram, O Sevastyanova… - Mutation Research …, 2007 - Elsevier
Acellular assay of calf thymus DNA±rat liver microsomal S9 fraction coupled with 32P-
postlabelling was used to study the genotoxic potential of organic compounds bound onto …

Risk assessment of environmental mixture effects

KA Heys, RF Shore, MG Pereira, KC Jones, FL Martin - RSC advances, 2016 - pubs.rsc.org
In the environment, organisms are exposed to a diverse array of chemicals in complex
mixtures. The majority of approaches that aim to assess the risk of environmental chemical …

A novel computational solution to the health risk assessment of air pollution via joint toxicity prediction: A case study on selected PAH binary mixtures in particulate …

X Liu, H Zhang, W Pan, Q Xue, J Fu, G Liu… - Ecotoxicology and …, 2019 - Elsevier
Regional haze episode has already caused overwhelming public concern. Unraveling the
health effects of the representative composition mixtures of atmospheric fine particulate …

New approaches to risk assessment of chemical mixtures

AW Hayes, R Li, J Hoeng, A Iskandar… - Toxicology …, 2019 - journals.sagepub.com
Assessing the risk of chemical mixtures is an intricate process that should integrate
published laboratory data; comparisons with the composition, toxicity, and functionality of …

[PDF][PDF] Uncertainty in msPAF-based ecotoxicological freshwater effect factors for chemicals with a non-specific mode of action in life cycle impact assessment

R Zelm, MAJ Huijbregts, JV Harbers, AM Wintersen… - 2007 - repository.ubn.ru.nl
Ecotoxicological effect factors are part of the analysis of relative impacts by chemical
contaminants on ecosystems. Uncertainty distributions, represented by the 90% confidence …

Effect of artificial mixtures of environmental polycyclic aromatic hydrocarbons present in coal tar, urban dust, and diesel exhaust particulates on MCF‐7 cells in culture

B Mahadevan, H Parsons, T Musafia… - Environmental and …, 2004 - Wiley Online Library
Human exposure to polycyclic aromatic hydrocarbons (PAHs) occurs through complex
mixtures. The National Institute of Standards and Technology has established standard …

[HTML][HTML] AhR-mediated activities of polycyclic aromatic compound (PAC) mixtures are predictable by the concept of concentration addition

M Larsson, JP Giesy, M Engwall - Environment international, 2014 - Elsevier
Risk assessments of polycyclic aromatic hydrocarbons (PAHs) are complicated because
these compounds exist in the environment as complex mixtures of hundreds of individual …

Environment impact and probabilistic health risks of PAHs in dusts surrounding an iron and steel enterprise

X Wei, C Ding, C Chen, L Zhu, G Zhang, Y Sun - Scientific Reports, 2021 - nature.com
Dust can be regarded as environmental medium that indicates the level and spatial
distribution of polycyclic aromatic hydrocarbons (PAHs) coming from different pollution …

Application of a semi-automated SOS chromotest for measuring genotoxicities of complex environmental mixtures containing polycyclic aromatic hydrocarbons

L Nylund, E Hakala, M Sorsa - Mutation Research/Reviews in Genetic …, 1992 - Elsevier
Soxhlet-extracted samples of standard reference materials (SRMs) 1649 (PART: urban
dust/organics) and 1650 (PAR2: diesel particulate matter) from the US Institute of Standards …

Tumors and DNA adducts in mice exposed to benzo [a] pyrene and coal tars: implications for risk assessment.

LS Goldstein, EH Weyand, S Safe… - Environmental …, 1998 - ehp.niehs.nih.gov
Current methods to estimate the quantitative cancer risk of complex mixtures of polycyclic
aromatic hydrocarbons (PAH) such as coal tar assume that overall potency can be derived …