An acellular assay to assess the genotoxicity of complex mixtures of organic pollutants bound on size segregated aerosol. Part I: DNA adducts

J Topinka, J Hovorka, A Milcova, J Schmuczerova… - Toxicology letters, 2010 - Elsevier
An acellular assay consisting of calf thymus DNA with/without rat liver microsomal S9
fraction was used to study the genotoxicity of complex mixtures of organic air pollutants …

Toxic equivalency factors (TEFs) and their use in ecological risk assessment: a successful method when used appropriately

JT Sanderson, M Berg - Human and Ecological Risk Assessment …, 1999 - Taylor & Francis
Great efforts have been made over the last decade to formulate sets of toxic equivalency
factors (TEFs) for an important group of persistent and toxic environmental contaminants …

[PDF][PDF] Human health hazard of polycyclic aromatic hydrocarbon in road dust in Ha Noi metropolis

VT Le Ha - Vietnam Journal of Science and Technology, 2016 - researchgate.net
This study investigates PAHs content in road dust of Hanoi metropolis, Vietnam. The
samples were colected from the roads around city and analyzed by gas chromatography …

Investigation of spatial and temporal variation of particulate matter in vitro genotoxicity and cytotoxicity in relation to the elemental composition

G Çakmak, PE Arı, E Emerce, A Arı, M Odabaşı… - … /Genetic Toxicology and …, 2019 - Elsevier
Even though the outdoor air pollution and its major component Particulate Matter (PM) are
recently classified as human carcinogen, attempts to elucidate the underlying mechanisms …

Risk assessment of lung cancer related to environmental PAH pollution sources

A Vyskocil, C Viau, M Camus - Human & experimental …, 2004 - journals.sagepub.com
We assessed the lung cancer risk in six localities with aluminium smelting activities and five
with other polycyclic aromatic hydrocarbon (PAH) pollution sources, using two quantitative …

Particle induced toxicity in relation to transition metal and polycyclic aromatic hydrocarbon contents

ME Gerlofs-Nijland, M Rummelhard… - … science & technology, 2009 - ACS Publications
Exposure to ambient particulate matter (PM) is statistically significantly associated with
morbidity and mortality. The objectives of this study were (a) to investigate in vivo pulmonary …

Uncertainty in msPAF‐based ecotoxicological effect factors for freshwater ecosystems in life cycle impact assessment

R Van Zelm, MAJ Huijbregts, JV Harbers… - Integrated …, 2007 - Wiley Online Library
Ecotoxicological effect factors are part of the analysis of relative impacts by chemical
contaminants on ecosystems. Uncertainty distributions, represented by the 90% confidence …

Coal mine fire effects on carcinogenicity and non-carcinogenicity human health risks

D Roy, G Singh, YC Seo - Environmental Pollution, 2019 - Elsevier
Atmospheric particulate matter (PM) pollution levels and human health risks resulting from
exposure to non-anthropogenic pollution sources, such as coal mine-fires, are serious …

p53 induction and cell viability modulation by genotoxic individual chemicals and mixtures

C Di Paolo, Y Müller, B Thalmann, H Hollert… - … Science and Pollution …, 2018 - Springer
The binding of the p53 tumor suppression protein to DNA response elements after genotoxic
stress can be quantified by cell-based reporter gene assays as a DNA damage endpoint …

[HTML][HTML] Application of new statistical distribution approaches for environmental mixture risk assessment: A case study

A Kienzler, S Bopp, M Halder, M Embry… - Science of The Total …, 2019 - Elsevier
Objectives There is growing evidence that single substances present below their individual
thresholds of effect may still contribute to combined effects. In component-based mixture risk …