The involvement of Cancer Stem Cells (CSCs) in tumor progression and tumor recurrence is
one of the most studied subjects in current cancer research. The CSC hypothesis states that …

Expansion of the undifferentiated stem cell phenotype is one of the most challenging
aspects in stem cell research. Clinical protocols for stem cell therapeutics will require …

Abstract Purpose of Review Adult stem cells play a key role in tissue regeneration and
cancer. To translate findings from stem cell biology into clinics, we require a quantitative …

The cancer stem cell hypothesis has gained currency in recent times but concerns remain
about its scientific foundations because of significant gaps that exist between research …

The cancer stem cell hypothesis suggests that tumors contain a small population of cancer
cells that have the ability to undergo symmetric self-renewing cell division. In tumors that …

Stem cells dynamics is an important field of research with promising clinical impacts. Due to
the revolutionary new technologies of biological data collection, an enormous amount of …

There is increasing evidence that the growth of human tumours is driven by a small
proportion of tumour stem cells with self-renewal properties. Multiplication of these cells …

Cancer has long been viewed as an exclusively genetic disorder. The model of
carcinogenesis, postulated by Nowell and Vogelstein, describes the formation of a tumor by …

Tumor growth, which plays a central role in cancer evolution, depends on both the internal
features of the cells, such as their ability for unlimited duplication, and the external …

Objective: In recent years, support has increased for the notion that a subpopulation of brain
tumour cells in possession of properties typically characteristic of stem cells is responsible …