Biomarkers to identify ILD and predict lung function decline in scleroderma lung disease or idiopathic pulmonary fibrosis.
B Kennedy, P Branagan, F Moloney… - … vasculitis, and diffuse …, 2015 - europepmc.org
Background SSc-ILD and IPF demonstrate significant morbidity and mortality. Predicting
disease progression is challenging in both diseases. Objectives We sought a serum …
disease progression is challenging in both diseases. Objectives We sought a serum …
Elevated serum Krebs von den Lungen-6 in early disease predicts subsequent deterioration of pulmonary function in patients with systemic sclerosis and interstitial …
M Kuwana, Y Shirai, T Takeuchi - The Journal of rheumatology, 2016 - jrheum.org
Objective. To identify predictors of poor prognosis in patients with systemic sclerosis (SSc)
associated with interstitial lung disease (ILD). Methods. Fifty patients with early-stage SSc …
associated with interstitial lung disease (ILD). Methods. Fifty patients with early-stage SSc …
[PDF][PDF] Follow-up of serum KL-6 lung fibrosis biomarker levels in 173 patients with systemic sclerosis
G Kumánovics, E Görbe, T Minier, D Simon… - Clin Exp …, 2014 - clinexprheumatol.org
Objective. A single-centre retrospective longitudinal study to investigate the predictive value
of KL-6 serum levels for the outcome of interstitial lung fibrosis in a large systemic sclerosis …
of KL-6 serum levels for the outcome of interstitial lung fibrosis in a large systemic sclerosis …
Serum KL-6 as a biomarker of progression at any time in fibrotic interstitial lung disease
LB Jehn, U Costabel, E Boerner, J Wälscher… - Journal of clinical …, 2023 - mdpi.com
The development of a progressive phenotype of interstitial lung disease (ILD) is still
unpredictable. Whereas tools to predict mortality in ILD exist, scores to predict disease …
unpredictable. Whereas tools to predict mortality in ILD exist, scores to predict disease …
Performance of candidate serum biomarkers for systemic sclerosis–associated interstitial lung disease
M Elhai, AM Hoffmann‐Vold, J Avouac… - Arthritis & …, 2019 - Wiley Online Library
Objective Interstitial lung disease (ILD) in systemic sclerosis (SS c) runs a highly variable
course, and prediction tools are highly desired. The aim of this study was to assess the …
course, and prediction tools are highly desired. The aim of this study was to assess the …
Serum interleukin 6 is predictive of early functional decline and mortality in interstitial lung disease associated with systemic sclerosis
A De Lauretis, P Sestini, P Pantelidis… - The Journal of …, 2013 - jrheum.org
Objective. Biomarkers of progression of interstitial lung disease (ILD) are needed to allow
early therapeutic intervention in patients with scleroderma-associated disease (SSc-ILD) …
early therapeutic intervention in patients with scleroderma-associated disease (SSc-ILD) …
[HTML][HTML] Serum KL-6 and surfactant protein-D as monitoring and predictive markers of interstitial lung disease in patients with systemic sclerosis and mixed connective …
H Yamakawa, E Hagiwara, H Kitamura… - Journal of thoracic …, 2017 - ncbi.nlm.nih.gov
Background Interstitial lung disease (ILD) is frequent complication of systemic sclerosis
(SSc) and mixed connective tissue disease (MCTD). The disease is heterogeneous, and its …
(SSc) and mixed connective tissue disease (MCTD). The disease is heterogeneous, and its …
Kinetic changes in serum KL-6 levels predict disease progression in patients with systemic sclerosis-associated interstitial lung disease
S Watanabe, K Kase, K Saeki, N Ohkura, A Murata… - Respiratory …, 2022 - Elsevier
Background The clinical course of patients with systemic sclerosis-associated interstitial
lung disease (SSc-ILD) is highly variable. The Krebs von den Lungen-6 (KL-6) glycoprotein …
lung disease (SSc-ILD) is highly variable. The Krebs von den Lungen-6 (KL-6) glycoprotein …
Baseline serum Krebs von den Lungen-6 as a biomarker for the disease progression in idiopathic pulmonary fibrosis
C Chung, J Kim, HS Cho, HC Kim - Scientific Reports, 2022 - nature.com
Disease progression (DP) is an important parameter for the prognosis of idiopathic
pulmonary fibrosis (IPF). This study aimed to evaluate the baseline serum biomarkers for …
pulmonary fibrosis (IPF). This study aimed to evaluate the baseline serum biomarkers for …
Importance of serial changes in biomarkers in idiopathic pulmonary fibrosis
A Sokai, K Tanizawa, T Handa, K Kanatani… - ERJ Open …, 2017 - Eur Respiratory Soc
The clinical significance of serial changes in serum biomarkers in patients with idiopathic
pulmonary fibrosis (IPF) remains to be established. This retrospective study was conducted …
pulmonary fibrosis (IPF) remains to be established. This retrospective study was conducted …
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