Regulation of monocyte chemoattractant protein 1 by cytokines and oxygen free radicals in rat hepatic fat-storing cells

Y Xu, M Rojkind, MJ Czaja - Gastroenterology, 1996 - Elsevier
BACKGROUND & AIMS: Monocyte chemoattractant protein 1 (MCP-1) is a potent monocyte/
macrophage chemoattractant expressed by fat-storing cells (FSCs) in rat models of liver …

Cultured human liver fat-storing cells produce monocyte chemotactic protein-1. Regulation by proinflammatory cytokines.

F Marra, AJ Valente, M Pinzani… - The Journal of clinical …, 1993 - Am Soc Clin Investig
Monocytes infiltrate the portal space during chronic liver inflammation. Monocyte
chemotactic protein-1 (MCP-1) is a cytokine that induces monocyte chemotaxis and …

Monocyte chemoattractant protein 1 (MCP‐1) expression occurs in toxic rat liver injury and human liver disease

MJ Czaja, A Geerts, J Xu… - Journal of leukocyte …, 1994 - Wiley Online Library
Considerable evidence suggests that monocytes/macrophages play a crucial role in the
process of liver injury and repair. Recent investigations have focused on the function of …

Expression of monocyte chemotactic protein-1 precedes monocyte recruitment in a rat model of acute liver injury, and is modulated by vitamin E.

F Marra, R DeFranco, C Grappone… - … Medicine: the Official …, 1999 - europepmc.org
Background Increased expression of monocyte chemotactic protein-1 (MCP-1) has been
indicated as a mechanism underlying leukocyte recruitment after liver injury. In this study we …

Hepatic monocyte chemoattractant protein-1 is upregulated by dietary cholesterol and contributes to liver steatosis

A Rull, F Rodríguez, G Aragonès, J Marsillach… - Cytokine, 2009 - Elsevier
To assess the role of monocyte chemoattractant protein-1 (MCP-1/CCL2) in the
development of fatty liver, we have used LDLr−/− mice as an animal model of high-fat, high …

Mesenteric adipose tissue‐derived monocyte chemoattractant protein‐1 plays a crucial role in adipose tissue macrophage migration and activation in obese mice

R Yu, CS Kim, BS Kwon, T Kawada - Obesity, 2006 - Wiley Online Library
Objective: To determine whether chemokines, which play a pivotal role in monocyte/
macrophage trafficking, modulate macrophage infiltration into and activation in the adipose …

Increased expression of monocyte chemotactic protein-1 during active hepatic fibrogenesis: correlation with monocyte infiltration.

F Marra, R DeFranco, C Grappone… - The American journal …, 1998 - ncbi.nlm.nih.gov
Abstract Monocyte chemotactic protein (MCP)-1 is a chemoattractant and activator for
circulating monocytes and T lymphocytes. We investigated MCP-1 protein and gene …

[HTML][HTML] Systemic MCP-1 levels derive mainly from injured liver and are associated with complications in cirrhosis

A Queck, H Bode, FE Uschner, MJ Brol, C Graf… - Frontiers in …, 2020 - frontiersin.org
Background and Aims: Monocyte chemotactic protein-1 (MCP-1) is a potent chemoattractant
for monocytes. It is involved in pathogenesis of several inflammatory diseases. Hepatic MCP …

Regulation of monocyte chemoattractant protein 1 (MCP-1) release by explants of human visceral adipose tissue

JN Fain, AK Madan - International Journal of Obesity, 2005 - nature.com
BACKGROUND: Monocyte chemoattractant protein-1 (MCP-1) is a chemokine involved in
monocyte recruitment during inflammation whose plasma level is elevated in obesity …

[HTML][HTML] Monocyte chemoattractant protein-1 is not required for liver regeneration after partial hepatectomy

SL Wyler, SL D'Ingillo, CL Lamb, KA Mitchell - Journal of Inflammation, 2016 - Springer
Background Liver regeneration following 70% partial hepatectomy (PH) requires the
coordinated expression of soluble mediators produced by macrophages. Monocyte …