[HTML][HTML] Advances in RSV vaccine research and development–a global agenda

D Higgins, C Trujillo, C Keech - Vaccine, 2016 - Elsevier
Respiratory syncytial virus (RSV) is an important cause of viral lower respiratory tract illness
in infants and children globally, but no vaccine is currently available to protect these …

[HTML][HTML] Strategic priorities for respiratory syncytial virus (RSV) vaccine development

LJ Anderson, PR Dormitzer, DJ Nokes, R Rappuoli… - Vaccine, 2013 - Elsevier
Although RSV has been a high priority for vaccine development, efforts to develop a safe
and effective vaccine have yet to lead to a licensed product. Clinical and epidemiologic …

A recombinant respiratory syncytial virus vaccine candidate attenuated by a low-fusion F protein is immunogenic and protective against challenge in cotton rats

CA Rostad, CC Stobart, BE Gilbert, RJ Pickles… - Journal of …, 2016 - Am Soc Microbiol
Although respiratory syncytial virus (RSV) is the leading cause of lower respiratory tract
infections in infants, a safe and effective vaccine is not yet available. Live-attenuated …

Summary of the Vaccines and Related Biological Products Advisory Committee meeting held to consider evaluation of vaccine candidates for the prevention of …

SK Browne, JA Beeler, JN Roberts - Vaccine, 2020 - Elsevier
Respiratory syncytial virus (RSV), is a common cause of serious acute lower respiratory tract
illness in infants and young children, causing substantial morbidity and mortality globally …

Challenges in developing a pediatric RSV vaccine

JH Schickli, F Dubovsky, RS Tang - Human vaccines, 2009 - Taylor & Francis
RSV bronchiolitis is the leading cause of infant hospitalization in industrialized countries.
There is an unmet need to prevent RSV lower respiratory tract infection in young infants …

[PDF][PDF] In hot pursuit of the first vaccine against respiratory syncytial virus

JY Kim, J Chang - Yonsei Medical Journal, 2016 - synapse.koreamed.org
Human respiratory syncytial virus (RSV) is the leading cause of severe lower respiratory
tract infection, such as bronchiolitis, bronchitis, or pneumonia, in both infants and the elderly …

Human and bovine respiratory syncytial virus vaccine research and development

G Meyer, M Deplanche, F Schelcher - … immunology, microbiology and …, 2008 - Elsevier
Human (HRSV) and bovine (BRSV) respiratory syncytial viruses (RSV) are two closely
related viruses, which are the most important causative agents of respiratory tract infections …

Understanding respiratory syncytial virus (RSV) vaccine development and aspects of disease pathogenesis

PA Jorquera, L Anderson, RA Tripp - Expert review of vaccines, 2016 - Taylor & Francis
Respiratory syncytial virus (RSV) is the most important cause of lower respiratory tract
infections causing bronchiolitis and some mortality in young children and the elderly …

Immunological goals for respiratory syncytial virus vaccine development

BS Graham - Current opinion in immunology, 2019 - Elsevier
Highlights•Immunological goals for vaccination depend on whether it is for primary induction
or boosting of pre-existing immunity.•Boosting neutralizing activity is the major goal for …

Hurdles in vaccine development against respiratory syncytial virus

M Shafique, MA Zahoor, MI Arshad… - The Burden of …, 2019 - books.google.com
Respiratory syncytial virus (RSV) infection is a major cause of severe respiratory disease in
infants and young children worldwide and also forms a serious threat for the elderly …