Respiratory syncytial virus vaccines: recent developments

PA Piedra - The Pediatric infectious disease journal, 2000 - journals.lww.com
Respiratory syncytial virus (RSV) is the principal pathogen associated with lower respiratory
tract illness (LRTI) in infants and children in the United States and in other industrialized …

Immunopathology of RSV infection: prospects for developing vaccines without this complication

SD Littel‐van den Hurk, JW Mapletoft… - Reviews in medical …, 2007 - Wiley Online Library
Respiratory syncytial virus is the most important cause of lower respiratory tract infection in
infants and young children. RSV clinical disease varies from rhinitis and otitis media to …

Development of mRNA vaccines against respiratory syncytial virus (RSV)

X Qiu, S Xu, Y Lu, Z Luo, Y Yan, C Wang, J Ji - Cytokine & Growth Factor …, 2022 - Elsevier
Respiratory syncytial virus (RSV) is a single-stranded negative-sense RNA virus that is the
primary etiologic pathogen of bronchitis and pneumonia in infants and the elderly. Currently …

Vaccines against respiratory syncytial virus: the time has finally come

BS Graham - Vaccine, 2016 - Elsevier
Respiratory syncytial virus causes a significant public health burden, particularly in very
young infants and the frail elderly. The legacy of enhanced RSV disease (ERD) from a …

Clinical experience with respiratory syncytial virus vaccines

PA Piedra - The Pediatric infectious disease journal, 2003 - journals.lww.com
Respiratorysyncytial virus (RSV) infection is at times associated with life-threatening lower
respiratory tract illness in infancy. Severe infection during the first year of life may be an …

The path to an RSV vaccine

CA Shaw, M Ciarlet, BW Cooper, L Dionigi… - Current opinion in …, 2013 - Elsevier
Highlights•Maternal immunization provides a path to early infant protection against
RSV.•Structure-based engineering overcomes the biochemical challenges of the RSV F …

Immunological properties of plaque purified strains of live attenuated respiratory syncytial virus (RSV) for human vaccine

ML Herlocher, M Ewasyshyn, S Sambhara… - Vaccine, 1999 - Elsevier
Respiratory syncytial virus (RSV) causes severe lower respiratory tract disease in infants,
young children, and the elderly. Efforts to develop satisfactory live or inactivated vaccines …

Nucleic acid-based vaccines targeting respiratory syncytial virus: delivering the goods

TRF Smith, K Schultheis… - Human vaccines & …, 2017 - Taylor & Francis
Respiratory syncytial virus (RSV) is a massive medical burden on a global scale. Infants,
children and the elderly represent the vulnerable populations. Currently there is no …

Progress in the development of respiratory syncytial virus and parainfluenza virus vaccines

AP Durbin, RA Karron - Clinical infectious diseases, 2003 - academic.oup.com
Respiratory syncytial virus (RSV) and human parainfluenza viruses (hPIVs) are leading
causes of viral lower respiratory tract illness in children and in high-risk adult populations …

Influence of live respiratory syncytial virus priming on the immune response generated by a recombinant vaccine candidate, BBG2Na

L Goestch, H Plotnicky-Gilquin, T Champion, A Beck… - Vaccine, 2000 - Elsevier
Respiratory syncytial virus is one of the major respiratory pathogens for infants and
immunocompromized children. With the exception of young children, all the population has …