Combination of immunotherapy with targeted therapy: theory and practice in metastatic melanoma

C Yu, X Liu, J Yang, M Zhang, H Jin, X Ma… - Frontiers in …, 2019 - frontiersin.org
Metastatic melanoma is the most aggressive and obstinate skin cancer with poor prognosis.
Variant novel applicable regimens have emerged during the past decades intensively, while …

Systemic therapy of metastatic melanoma: on the road to cure

J Steininger, FF Gellrich, A Schulz, D Westphal… - Cancers, 2021 - mdpi.com
Simple Summary Malignant melanoma is more dangerous than most other skin cancers due
to its ability to spread early and aggressively. Until the development of new therapeutic …

Immunotherapy for advanced melanoma: fulfilling the promise

H Gogas, A Polyzos, J Kirkwood - Cancer treatment reviews, 2013 - Elsevier
The incidence of melanoma is increasing worldwide and despite early detection and
intervention, the number of patients dying from metastatic disease continues to rise. The …

Advances in targeted therapy and immunotherapy for melanoma

Z Qin, M Zheng - Experimental and Therapeutic …, 2023 - spandidos-publications.com
Melanoma is the most aggressive and deadly type of skin cancer and is known for its poor
prognosis as soon as metastasis occurs. Since 2011, new and effective therapies for …

Therapeutic advances and treatment options in metastatic melanoma

DB Johnson, JA Sosman - JAMA oncology, 2015 - jamanetwork.com
Over the past several years, management of advanced melanoma has been transformed by
the development and approval of novel therapeutic approaches. Genetically targeted …

The current state of treatment and future directions in cutaneous malignant melanoma

M Ernst, A Giubellino - Biomedicines, 2022 - mdpi.com
Malignant melanoma is the leading cause of death among cutaneous malignancies. While
its incidence is increasing, the most recent cancer statistics show a small but clear decrease …

Current systemic therapy for metastatic melanoma

SS Agarwala - Expert review of anticancer therapy, 2009 - Taylor & Francis
Metastatic melanoma remains a lethal disease with a long-term remission rate of less than
10%. Despite many years of research, there has not been a new drug approved in this …

Immunotherapy of melanoma: present options and future promises

A Rotte, M Bhandaru, Y Zhou, KJ McElwee - Cancer and Metastasis …, 2015 - Springer
Metastatic melanoma is notorious for its immune evasion and resistance to conventional
chemotherapy. The recent success of ipilimumab, a human monoclonal antibody against …

Treatment of metastatic melanoma with a combination of immunotherapies and molecularly targeted therapies

T Rager, A Eckburg, M Patel, R Qiu, S Gantiwala… - Cancers, 2022 - mdpi.com
Simple Summary Immunotherapies and molecularly targeted therapies have drastically
changed the therapeutic approach for unresectable advanced or metastatic melanoma. The …

Immunotherapy in melanoma: recent advances and future directions

A Knight, L Karapetyan, JM Kirkwood - Cancers, 2023 - mdpi.com
Simple Summary Immunotherapy has demonstrated the ability to reduce the risk of
recurrence for melanoma following surgical resection and improve survival in patients with …