Heterologous gene expression in filamentous fungi

X Su, G Schmitz, M Zhang, RI Mackie… - Advances in applied …, 2012 - Elsevier
Filamentous fungi are critical to production of many commercial enzymes and organic
compounds. Fungal-based systems have several advantages over bacterial-based systems …

Heterologous protein production in filamentous fungi

D Liu, S Garrigues, RP de Vries - Applied microbiology and biotechnology, 2023 - Springer
Filamentous fungi are able to produce a wide range of valuable proteins and enzymes for
many industrial applications. Recent advances in fungal genomics and experimental …

Filamentous fungi as cell factories for heterologous protein production

PJ Punt, N van Biezen, A Conesa, A Albers… - Trends in …, 2002 - cell.com
Filamentous fungi have been used as sources of metabolites and enzymes for centuries. For
about two decades, molecular genetic tools have enabled us to use these organisms to …

Gene expression systems for filamentous fungi

T Fowler, RM Berka - Current Opinion in Biotechnology, 1991 - Elsevier
The extraordinary capacity of filamentous fungi to produce large quantities of extracellular
protein, together with the advent of DNA-mediated fungal transformation, has resulted in …

Approaches for refining heterologous protein production in filamentous fungi

R Sharma, M Katoch, PS Srivastava… - World Journal of …, 2009 - Springer
Fungi combine the advantages of a microbial system such as a simple fermentability with the
capability of secreting proteins that are modified according to a general eukaryotic scheme …

Production of recombinant proteins by filamentous fungi

OP Ward - Biotechnology advances, 2012 - Elsevier
The initial focus of recombinant protein production by filamentous fungi related to exploiting
the extraordinary extracellular enzyme synthesis and secretion machinery of industrial …

Heterologous protein expression in filamentous fungi

KMH Nevalainen, VSJ Te'o, PL Bergquist - Trends in biotechnology, 2005 - cell.com
Filamentous fungi are commonly used in the fermentation industry for the large-scale
production of proteins–mainly industrial enzymes. Recent advances in fungal genomics and …

[PDF][PDF] 9 Heterologous Protein Production by Filamentous Fungi

DJ Jeenes, DA Mackenzie, IN Roberts… - Biotechnology and …, 1991 - Taylor & Francis
Filamentous fungi have found application in many technologies. These include the
production of antibiotics, enzymes, organic acids, foods and beverages, and …

Making recombinant proteins in filamentous fungi-are we expecting too much?

H Nevalainen, R Peterson - Frontiers in microbiology, 2014 - frontiersin.org
Hosts used for the production of recombinant proteins are typically high-protein secreting
mutant strains that have been selected for a specific purpose, such as efficient production of …

Aspergillus: A powerful protein production platform

F Ntana, UH Mortensen, C Sarazin, R Figge - Catalysts, 2020 - mdpi.com
Aspergilli have been widely used in the production of organic acids, enzymes, and
secondary metabolites for almost a century. Today, several GRAS (generally recognized as …