[HTML][HTML] Triclocarban disrupts the epigenetic status of neuronal cells and induces AHR/CAR-mediated apoptosis

M Kajta, A Wnuk, J Rzemieniec, W Lason… - Molecular …, 2019 - Springer
Triclocarban is a phenyl ether that has recently been classified as a contaminant of
emerging concern. Evidence shows that triclocarban is present in human tissues, but little is …

Triclocarban impairs autophagy in neuronal cells and disrupts estrogen receptor signaling via hypermethylation of specific genes

M Kajta, J Rzemieniec, A Wnuk, W Lasoń - Science of the Total …, 2020 - Elsevier
Although an increasing body of evidence suggests that triclocarban, a phenyl ether
classified as a contaminant of emerging concern, presents a risk to development, there is …

[HTML][HTML] Prenatal exposure to triclocarban impairs ESR1 signaling and disrupts epigenetic status in sex-specific ways as well as dysregulates the expression of …

A Wnuk, J Rzemieniec, K Przepiórska… - International Journal of …, 2021 - mdpi.com
Triclocarban is a highly effective and broadly used antimicrobial agent. Humans are
continually exposed to triclocarban, but the safety of prenatal exposure to triclocarban in the …

Dose-dependent effects of triclocarban exposure on lipid homeostasis in rats

M Dong, X Xu, Q Huang, H Lei, G Xu, J Ma… - Chemical research in …, 2019 - ACS Publications
Environmental exposure to triclocarban (TCC), a common antibacterial agent widely used in
thousands of personal care products, poses a potential risk for human health. Previous in …

[HTML][HTML] Integrated multi-omics approaches reveal the neurotoxicity of triclocarban in mouse brain

Q Song, C Hu, X Zhang, P Ji, Y Li, H Peng… - Environment …, 2024 - Elsevier
Triclocarban (TCC) is an antimicrobial ingredient that commonly incorporated in many
household and personal care products, raising public concerns about its potential health …

Biomarkers of exposure to triclocarban in urine and serum

X Ye, X Zhou, J Furr, KC Ahn, BD Hammock, EL Gray… - Toxicology, 2011 - Elsevier
Abstract 3, 4, 4′-Trichlorocarbanilide (triclocarban, TCC) is widely used as an antimicrobial
agent in a variety of consumer and personal care products. TCC is considered a potential …

[HTML][HTML] Triclocarban mediates induction of xenobiotic metabolism through activation of the constitutive androstane receptor and the estrogen receptor alpha

MF Yueh, T Li, RM Evans, B Hammock, RH Tukey - PloS one, 2012 - journals.plos.org
Triclocarban (3, 4, 4′-trichlorocarbanilide, TCC) is used as a broad-based antimicrobial
agent that is commonly added to personal hygiene products. Because of its extensive use in …

[HTML][HTML] Acute exposure of triclocarban affects early embryo development in mouse through disrupting maternal-to-zygotic transition and epigenetic modifications

ZM Ding, SK Wang, SX Zhang, YW Chen… - Ecotoxicology and …, 2023 - Elsevier
Triclocarban (TCC) is a broad-spectrum antibacterial agent used globally, and high
concentrations of this harmful chemical exist in the environment. The human body is directly …

Triclosan activates aryl hydrocarbon receptor (AhR)-dependent apoptosis and affects Cyp1a1 and Cyp1b1 expression in mouse neocortical neurons

KA Szychowski, A Wnuk, M Kajta, AK Wójtowicz - Environmental research, 2016 - Elsevier
Triclosan (TCS) is an antimicrobial agent that is used extensively in personal care and in
sanitizing products, such as soaps, toothpastes, and hair products. A number of studies have …

[HTML][HTML] Maternal exposure to an environmentally relevant dose of triclocarban results in perinatal exposure and potential alterations in offspring development in the …

HA Enright, MJS Falso, MA Malfatti, V Lao, EA Kuhn… - PloS one, 2017 - journals.plos.org
Triclocarban (TCC) is among the top 10 most commonly detected wastewater contaminants
in both concentration and frequency. Its presence in water, as well as its propensity to …