Objectives: Sepsis-related lung injury is the most common and morbid form of acute lung
injury. The objective of this study was to develop an ovine model of septic acute lung injury …

Objective: The common denominator in most forms of ventilator-induced lung injury is an
intense inflammatory response mediated by neutrophils. PET with [18 F] fluoro-2-deoxy-D …

This review focuses on methods to image acute lung inflammation with Positron Emission
Tomography (PET). Four approaches are discussed that differ for biologic function of the …

PET with 18F-FDG allows for noninvasive assessment of regional lung metabolism reflective
of neutrophilic inflammation. This study aimed at determining during early acute lung injury …

Purpose This study investigates whether positron emission tomography (PET) can be used
to monitor the inflammatory response and its correlation with the later fibroproliferative …

Objective: PET with [18 F] fluoro-2-deoxy-D-glucose can be used to image cellular
metabolism, which during lung inflammation mainly reflects neutrophil activity, allowing the …

Background: Mechanical ventilation (MV) may initiate or worsen lung injury, so-called
ventilator-induced lung injury (VILI). Although different mechanisms of VILI have been …

VENTILATION HETEROGENEITY is an established marker of pulmonary dysfunction in
asthma and other conditions such as acute respiratory distress syndrome (ARDS) and …

Regional pulmonary perfusion (Q) has been investigated using blood volume (Fb) imaging
as an easier-to-measure surrogate. However, it is unclear if changing pulmonary conditions …

Purpose To image inflammation and monitor therapeutic response to anti-inflammatory
intervention using 2-deoxy-2-[18F] fluoro-D-glucose ([18F] FDG) positron emission …