[引用][C] Minh C. Tran 1Ε, Douglas C. Crockett 1Ε, Tu K. Tran, Phi A. Phan 1Ε, Formenti Federico

R Bruce, G Perchiazzi, SJ Payne, AD Farmery - Scientific Reports, 2024

Modeling of Tracer Transport Delays for Improved Quantification of Regional Pulmonary 18F-FDG Kinetics, Vascular Transit Times, and Perfusion

TJ Wellman, T Winkler, MF Vidal Melo - Annals of biomedical engineering, 2015 - Springer
Abstract 18 F-FDG-PET is increasingly used to assess pulmonary inflammatory cell activity.
However, current models of pulmonary 18 F-FDG kinetics do not account for delays in 18 F …

Quantitative analysis of regional lung ventilation and perfusion PET with 68Ga-labelled tracers

L Oehme, K Zöphel, E Golgor, M Andreeff… - Nuclear Medicine …, 2014 - journals.lww.com
Methods Fifty-three patients (24 male and 29 female) underwent lung scintigraphy with 68
Ga-labelled radiopharmaceuticals. 68 Ga Galligas and B20 microspheres used for V and Q …

Lung metabolic activation as an early biomarker of acute respiratory distress syndrome and local gene expression heterogeneity

TJ Wellman, N De Prost, M Tucci, T Winkler… - …, 2016 - pubs.asahq.org
Background Acute respiratory distress syndrome (ARDS) is an inflammatory condition
comprising diffuse lung edema and alveolar damage. ARDS frequently results from regional …

[HTML][HTML] Reproducibility of compartmental modelling of 18F-FDG PET/CT to evaluate lung inflammation

LD Vass, S Lee, FJ Wilson, M Fisk, J Cheriyan… - EJNMMI physics, 2019 - Springer
Introduction Compartmental modelling is an established method of quantifying 18 F-FDG
uptake; however, only recently has it been applied to evaluate pulmonary inflammation …

[HTML][HTML] Advances in PET to assess pulmonary inflammation: a systematic review

L Vass, M Fisk, S Lee, FJ Wilson, J Cheriyan… - European Journal of …, 2020 - Elsevier
Background Respiratory diseases are one of the leading causes of death worldwide, yet
effective treatment options remain limited. Although inflammation is thought to be a key …

Noninvasive quantitative assessment of pulmonary blood flow with 18F-FDG PET

C Pouzot, JC Richard, A Gros, N Costes… - Journal of Nuclear …, 2013 - Soc Nuclear Med
Pulmonary blood flow (PBF) is a critical determinant of oxygenation during acute lung injury
(ALI). PET/CT with 18F-FDG allows the assessment of both lung aeration and neutrophil …

Micro-Autoradiographic Assessment of Cell Types Contributing to 2-Deoxy-2-[18F]Fluoro-d-Glucose Uptake During Ventilator-Induced and Endotoxemic Lung Injury

D Saha, K Takahashi, N de Prost, T Winkler… - Molecular imaging and …, 2013 - Springer
Purpose The aim of the study was to use micro-autoradiography to investigate the lung cell
types responsible for 2-deoxy-2-[18 F] fluoro-d-glucose (FDG) uptake in murine models of …

Interaction between regional lung volumes and ventilator-induced lung injury in the normal and endotoxemic lung

S Yen, M Preissner, E Bennett… - … of Physiology-Lung …, 2020 - journals.physiology.org
Both overdistension and atelectasis contribute to lung injury and mortality during mechanical
ventilation. It has been proposed that combinations of tidal volume and end-expiratory lung …

Non-invasive quantification of acute macrophagic lung inflammation with [11C](R)-PK11195 using a three-tissue compartment kinetic model in experimental acute …

L Bitker, F Dhelft, S Lancelot, D Le Bars… - European Journal of …, 2022 - Springer
Purpose Imaging of acute lung inflammation is pivotal to evaluate innovative ventilation
strategies. We aimed to develop and validate a three-tissue compartment kinetic model …