Positron emission tomography (PET) provides three-dimensional images of the distributions
of radionuclides that have been inhaled or injected into the lungs. By using radionuclides …

In this article we review some of the main findings obtained by Computed Tomography (CT)
and Positron Emission Tomography (PET) concerning the pathophysiology of Acute …

The lobar and cephalocaudal distribution of aerated and nonaerated lung and of PEEP-
induced alveolar recruitment is unknown in acute lung injury (ALI). Dimensions of the lungs …

Background Dynamic single-slice CT (dCT) is increasingly used to examine the intra-tidal,
physiological variation in aeration and lung density in experimental lung injury. The ability of …

In six male anesthetized, tracheotomized, and mechanically ventilated rabbits, we imaged
subpleural alveoli under microscopic view (60×) through a “pleural window” obtained by …

Lung inflammatory diseases contribute significantly to the socioeconomic burden of disease.
Yet very few new, effective therapies for respiratory disease have been approved for use. A …

Objective The aims of this study were to investigate the ability of contrast-enhanced dual-
energy computed tomography (DECT) for assessing regional perfusion in a model of acute …

Background Benefits of variable mechanical ventilation based on the physiological
breathing pattern have been observed both in healthy and injured lungs. These benefits …

Ventilator-induced lung injury (VILI) can be life-threatening and it is important to prevent the
development of VILI. It remains unclear whether the prone position affects neutrophilic …

Background Real-time bedside information on regional ventilation and perfusion during
mechanical ventilation (MV) may help to elucidate the physiological and pathophysiological …