Recent PET imaging data from bronchoconstricted sheep (Vidal Melo et al., 2005) showed
that V˙/Q˙ distributions were bimodal and topographically patchy, but including a substantial …

Background Lung strain, defined as the ratio between end-inspiratory volume and functional
residual capacity, is a marker of the mechanical load during ventilation. However, changes …

Objectives: Positive pressure ventilation exposes the lung to mechanical stresses that can
exacerbate injury. The exact mechanism of this pathologic process remains elusive. The …

Acute respiratory distress syndrome (ARDS) is a major cause of mortality in critically ill
patients. Patients are currently managed by protective ventilation and alveolar recruitment …

Background An inflammatory reaction in the airways and lung parenchyma, comprised
mainly of neutrophils and alveolar macrophages, is present in some patients with chronic …

Purpose It has recently been recognized that PET/CT may play a role in diffuse parenchymal
lung disease. However, interpretation can be confounded due to the variability in lung …

To determine the spatial distributions of pulmonary perfusion, shunt, and ventilation, we
developed a compartmental model of regional 13N-labeled molecular nitrogen (13NN) …

Lung recruitment maneuvers can help open collapsed lung units for sufficient oxygenation,
and positive end expiratory pressure (PEEP) is used to keep the lung open after recruitment …

Modern ventilatory strategies are based on the assumption that lung terminal airspaces act
as isotropic balloons that progressively accommodate gas. Phase contrast synchrotron …

2005; 62: 630–634. 6. Johnson HJ, Christensen GE. Consistent landmark and intensity-
based image registration. IEEE Trans Med Imaging 2002; 21: 450–461. 7. Kaczka DW, Cao …