Heparan sulfate proteoglycans are ubiquitously found at the cell surface and extracellular
matrix in all the animal species. This review will focus on the structural characteristics of the …

Heparan sulfate proteoglycans are complex molecules composed of a core protein with
covalently attached glycosaminoglycan chains. While the protein part determines …

Proteoglycans are abundant components of the cell surface and extracellular matrix that
mediate critical interactions between cells and their environment. They play a variety of …

Heparan sulfate (HS) proteoglycans (PGs) are ubiquitously expressed on cell surfaces and
in the extracellular matrix of most animal tissues, having essential functions in development …

Heparan sulfate (HS) proteoglycans at cell surfaces and in the extracellular matrix of most
animal tissues are essential in development and homeostasis, and variously implicated in …

Heparan sulfate proteoglycans are found at the cell surface and in the extracellular matrix,
where they interact with a plethora of ligands. Over the last decade, new insights have …

Numerous proteins, including cytokines and chemokines, enzymes and enzyme inhibitors,
extracellular matrix proteins, and membrane receptors, bind heparin. Although they are …

Heparan sulfate (HS) is a component of cell surface and matrix-associated proteoglycans
(HSPGs) that, collectively, play crucial roles in many physiologic processes including cell …

Heparan sulfate proteoglycans consist of a small family of proteins decorated with one or
more covalently attached heparan sulfate glycosaminoglycan chains. These chains have …

Heparan sulfate proteoglycans are a remarkably diverse family of glycosaminoglycan-
bearing protein cores that include the syndecans, the glypicans, perlecan, agrin, and …