Tissue destruction at the primary site of a spinal cord injury leads to persistent necrosis that
progressively enlarges the lesion. Steroids attenuate this necrotizing process and promote …

This review examines, in a condensed manner, many of the major achievements related to
spinal cord injury research during the last quarter century. Most of the advances have been …

There is evidence from both clinical and experimental studies that the spinal cord suffers
both primary and secondary damage after acute spinal cord injury. The pathophysiology of …

In 50 postmortem injured cords that we have examined with detailed magnetic resonance
imaging (MRI) and histopathologic analysis, a number of new and clinically important …

J. Douglas Balentine, MD, D. Un. Paris (Sc.) losed injuries of the spinal cord, as characteristi-
Clo cally produced by vehicular accidents, falls, and falling objects, are subjected to a …

Spinal cord injury is frequently followed by the loss of supraspinal control of sensory,
autonomic and motor functions at the sublesional level. In order to enhance recovery in …

This article reviews the pathology of human spinal cord injury (SCI), focusing on potential
differences between humans and experimental animals, as well as on aspects that may …

Spinal cord injury (SCI) triggers a complex cascade of molecular and chemical events that
leads to progressive cell loss and tissue damage. 1, 2 Nearly a century of fundamental basic …

Clinical management of spinal cord injury (SCI) has significantly improved its general
prognosis. However, to date, traumatic paraplegia and tetraplegia remain incurable, despite …

Every year in the United States spinal cord injuries (SCIs) occur in approximately 12000
individuals, resulting in chronic, debilitating functional deficits in most of these patients …