Pancreatic neuroendocrine tumors: molecular mechanisms and therapeutic targets

CK Maharjan, PH Ear, CG Tran, JR Howe… - Cancers, 2021 - mdpi.com
Simple Summary Pancreatic neuroendocrine tumors (pNETs) are rare, indolent cancers
whose causation is only partly understood. An increasing number of studies have uncovered …

[HTML][HTML] Insights into the biology and treatment strategies of pancreatic neuroendocrine tumors

JL Buicko, BM Finnerty, T Zhang, BJ Kim… - Annals of pancreatic …, 2019 - ncbi.nlm.nih.gov
Pancreatic neuroendocrine tumors (PNETs) are the second most common primary
pancreatic neoplasms after pancreatic ductal adenocarcinoma. PNETs present with widely …

Translational diagnostics and therapeutics in pancreatic neuroendocrine tumors

JE Maxwell, SK Sherman, JR Howe - Clinical cancer research, 2016 - AACR
Pancreatic neuroendocrine tumors (PNET) are rare tumors, but have been increasing in
incidence. Although typically thought of as indolent, more than half of patients present with …

Pancreatic neuroendocrine tumors: a comprehensive review

C Zhou, J Zhang, Y Zheng, Z Zhu - International journal of …, 2012 - Wiley Online Library
Pancreatic neuroendocrine tumors (NETs) are a heterogeneous group of tumors. Despite
being relatively rare, representing just 1–2% of all pancreatic neoplasms, the incidence of …

The evolving (epi) genetic landscape of pancreatic neuroendocrine tumours

CP Pipinikas, AM Berner, T Sposito… - Endocrine-related …, 2019 - erc.bioscientifica.com
Neuroendocrine neoplasms (NENs) are a relatively rare group of heterogeneous tumours
originating from neuroendocrine cells found throughout the body. Pancreatic NENs …

Current understanding of the molecular biology of pancreatic neuroendocrine tumors

J Zhang, R Francois, R Iyer, M Seshadri… - Journal of the …, 2013 - academic.oup.com
Pancreatic neuroendocrine tumors (PanNETs) are complicated and often deadly
neoplasms. A recent increased understanding of their molecular biology has contributed to …

[HTML][HTML] Update on pancreatic neuroendocrine tumors

LR McKenna, BH Edil - Gland surgery, 2014 - ncbi.nlm.nih.gov
Pancreatic neuroendocrine tumors (pNETs) are relatively rare tumors comprising 1-2% of all
pancreas neoplasms. In the last 10 years our understanding of this disease has increased …

[HTML][HTML] Pancreatic neuroendocrine tumors: Therapeutic challenges and research limitations

GB Mpilla, PA Philip, B El-Rayes… - World Journal of …, 2020 - ncbi.nlm.nih.gov
Pancreatic neuroendocrine tumors (PNETs) are known to be the second most common
epithelial malignancy of the pancreas. PNETs can be listed among the slowest growing as …

Well-differentiated pancreatic neuroendocrine tumors: from genetics to therapy

RF De Wilde, BH Edil, RH Hruban… - Nature Reviews …, 2012 - nature.com
Well-differentiated pancreatic neuroendocrine tumors (PanNETs) comprise∼ 1–3% of
pancreatic neoplasms. Although long considered as reasonably benign lesions, PanNETs …

[HTML][HTML] Pancreatic neuroendocrine tumors: biology, diagnosis, and treatment

C Ro, W Chai, EY Victoria, R Yu - Chinese journal of cancer, 2013 - ncbi.nlm.nih.gov
Pancreatic neuroendocrine tumors (PNETs), a group of endocrine tumors arising in the
pancreas, are among the most common neuroendocrine tumors. The genetic causes of …