NORDIL-the Nordic diltiazem intervention study was started in September 1992. This trial is
a prospective randomized open blinded-endpoint (PROBE) multicenter, parallel-group study …

Background The aim of the Nordic Diltiazem (NORDIL) Study was to compare patients with
essential hypertension receiving calcium-antagonist-based treatment with diltiazem and …

The benefits of antihypertensive drug therapy have been documented in a large number of
intervention trials [1]. The relative benefit of lowering the diastolic blood pressure by 5–6 …

Background Calcium antagonists are a first-line treatment for hypertension. The
effectiveness of diltiazem, a non-dihydropyridine calcium antagonist, in reducing …

The aim of the Nordic Diltiazem (NORDIL) Study was to compare cardiovascular morbidity
and mortality in calcium-antagonist-based treatment with diltiazem and conventional …

Diltiazem hydrochloride is a benzothiazepine derivative calcium‐channel blocker with
proven antianginal and antihypertensive capabilities. Its primary mechanism of action is …

The objective was to evaluate the dose-related efficacy/tolerance profile of 240, 300, 360,
and 420 mg diltiazem slow-release, once-daily (OD) doses, with emphasis on the 300 mg …

Although calcium channel blockers were only recently approved for antihypertensive
therapy, 10 years of data have demonstrated their beneficial effects. Among the available …

In a randomized, double-blind, parallel group study, diltiazem was compared with
metoprolol as add-on therapy to diuretic treatment in 115 patients with hypertension …

This is a comment on" Review: calcium antagonists and diuretics; a useful combination in
the management of hypertension?" J Hum Hypertens. 1996 Jul; 10 (7): 441-2. This is a …