Current insights into the “antiphospholipid” syndrome: clinical, immunological, and molecular aspects
DA Kandiah, A Sali, Y Sheng, EJ Victoria… - Advances in …, 1998 - Elsevier
Publisher Summary Antiphospholipid (aPL) antibodies are found in normal individuals, and
can be divided into two main groups, classified according to their association with …
can be divided into two main groups, classified according to their association with …
Thrombogenic Properties of Murine Anti-Cardiolipin Antibodies Induced by β2 Glycoprotein 1 and Human Immunoglobulin G Antiphospholipid Antibodies
SS Pierangeli, XW Liu, G Anderson, JH Barker… - Circulation, 1996 - Am Heart Assoc
Background Recurrent arterial thrombosis and venous thrombosis are frequent
complications of the antiphospholipid syndrome (APS). Patients produce anti-cardiolipin …
complications of the antiphospholipid syndrome (APS). Patients produce anti-cardiolipin …
Antibodies to phospholipid-binding plasma proteins and occurrence of thrombosis in patients with systemic lupus erythematosus
M Puurunen, O Vaarala, H Julkunen, K Aho… - Clinical immunology and …, 1996 - Elsevier
There is accumulating evidence that anti-phospholipid (aPL) antibodies in the sera of
patients with autoimmune diseases bind to a complex of anionic phospholipids and plasma …
patients with autoimmune diseases bind to a complex of anionic phospholipids and plasma …
Anti-phospholipid antibodies are directed against a complex antigen that includes a lipid-binding inhibitor of coagulation: beta 2-glycoprotein I (apolipoprotein H).
HP McNeil, RJ Simpson… - Proceedings of the …, 1990 - National Acad Sciences
Anti-phospholipid (aPL) antibodies that exhibit binding in cardiolipin (CL) ELISA can be
purified to greater than 95% purity by sequential phospholipid affinity and ion-exchange …
purified to greater than 95% purity by sequential phospholipid affinity and ion-exchange …
Lupus anticoagulant activity is frequently dependent on the presence of β2-glycoprotein I
JD Oostin, RHWM Derksen, HTI Entjes… - Thrombosis and …, 1992 - thieme-connect.com
Antiphospholipid antibodies (aPL) are defined by anticardioli-pin antibody (aCL) ELISA and
prolongation of phospholipid dependent coagulation assays (lupus anticoagulant; LAC). For …
prolongation of phospholipid dependent coagulation assays (lupus anticoagulant; LAC). For …
Prothrombin binds to the surface of apoptotic, but not viable, cells and serves as a target of lupus anticoagulant autoantibodies
P D'Agnillo, JS Levine, R Subang… - The Journal of …, 2003 - journals.aai.org
Anti-phospholipid Ab (aPL) are a heterogeneous group of autoantibodies directed against
various combinations of phospholipids (PL) and PL-binding proteins. Lupus anticoagulant …
various combinations of phospholipids (PL) and PL-binding proteins. Lupus anticoagulant …
Proof-of-concept study demonstrating the pathogenicity of affinity-purified IgG antibodies directed to domain I of β 2 -glycoprotein I in a mouse model of …
C Pericleous, P Ruiz-Limon, Z Romay-Penabad… - …, 2015 - academic.oup.com
Objective. IgG aPL against domain I of β 2-glycoprotein I (β 2 GPI)[anti-DI (aDI)] is
associated with the pathogenesis of APS, an autoimmune disease defined by thrombosis …
associated with the pathogenesis of APS, an autoimmune disease defined by thrombosis …
Endothelial cells as target for antiphospholipid antibodies. Human Polyclonal and Monoclonal Anti‐β2‐Glycoprotein I Antibodies React In Vitro with Endothelial Cells Through …
ND Papa, L Guidali, A Sala, C Buccellati… - … : Official Journal of …, 1997 - Wiley Online Library
Objective. To investigate the ability of human anti‐β2‐glycoprotein I (anti‐β2GPI) antibodies
to recognize the cofactor adherent on endothelial cells (EC) and to modulate endothelial …
to recognize the cofactor adherent on endothelial cells (EC) and to modulate endothelial …
Autoantibodies to phospholipid-binding plasma proteins in patients with thrombosis and phospholipid-reactive antibodies
V Pengo, A Biasiolo, T Brocco… - Thrombosis and …, 1996 - thieme-connect.com
Anti-phospholipid (aPL) antibodies are defined as antibodies detected in systems employing
phospholipids (PL). This general definition is misleading as it comprises a large group of …
phospholipids (PL). This general definition is misleading as it comprises a large group of …
Synchronized inhibition of the phospholipid mediated autoactivation of factor XII in plasma by β2-glycoprotein I and anti-β2-glycoprotein I
I Schousboe, MS Rasmussen - Thrombosis and haemostasis, 1995 - thieme-connect.com
Lupus anticoagulants are a group of antibodies commonly found in patients with
autoimmune diseases such as systemic lupus erythematosus. Lupus anticoagulants inhibit …
autoimmune diseases such as systemic lupus erythematosus. Lupus anticoagulants inhibit …