Recent advancements in the molecular genetics of left ventricular noncompaction cardiomyopathy

X Dong, P Fan, T Tian, Y Yang, Y Xiao, K Yang, Y Liu… - Clinica Chimica …, 2017 - Elsevier
Left ventricular noncompaction cardiomyopathy (LVNC) is a myocardial disorder
characterized by prominent and excessive trabeculations with deep recesses in the …

The importance of genetic counseling, DNA diagnostics, and cardiologic family screening in left ventricular noncompaction cardiomyopathy

YM Hoedemaekers, K Caliskan, M Michels… - Circulation …, 2010 - Am Heart Assoc
Background—Left ventricular (LV) noncompaction (LVNC) is a distinct cardiomyopathy
featuring a thickened bilayered LV wall consisting of a thick endocardial layer with …

The current approach to diagnosis and management of left ventricular noncompaction cardiomyopathy: review of the literature

CE Bennett, R Freudenberger - Cardiology Research and …, 2016 - Wiley Online Library
Isolated left ventricular noncompaction (LVNC) is a genetic cardiomyopathy characterized
by prominent ventricular trabeculations and deep intertrabecular recesses, or sinusoids, in …

Clinical genetics and outcome of left ventricular non-compaction cardiomyopathy

F Sedaghat-Hamedani, J Haas, F Zhu… - European heart …, 2017 - academic.oup.com
Aims In this study, we aimed to clinically and genetically characterize LVNC patients and
investigate the prevalence of variants in known and novel LVNC disease genes. Introduction …

Left ventricular noncompaction cardiomyopathy: New clues in a not so new disease?

JL Jefferies - Journal of the American Heart Association, 2021 - Am Heart Assoc
Left ventricular noncompaction cardiomyopathy (LVNC) remains a largely underinvestigated
and poorly understood diagnosis. The number of peer-reviewed articles published on LVNC …

Left ventricular noncompaction

F Ichida - Circulation Journal, 2009 - jstage.jst.go.jp
Left ventricular noncompaction (LVNC) is a recently defined cardiomyopathy characterized
by a pattern of prominent trabecular meshwork and deep intertrabecular recesses, and is …

Sarcomere gene mutations in isolated left ventricular noncompaction cardiomyopathy do not predict clinical phenotype

S Probst, E Oechslin, P Schuler… - Circulation …, 2011 - Am Heart Assoc
Background—Left ventricular noncompaction of the myocardium (LVNC) has been
recognized as a cardiomyopathy with a genetic etiology. Mutations in genes encoding …

Isolated left ventricular noncompaction: what do we really know?

F Peters, BK Khandheria - Current cardiology reports, 2012 - Springer
Isolated left ventricular noncompaction (ILVNC) is a myocardial disorder thought to occur as
a result of an arrest in embryogenesis. Recently, it has been classified as a genetic …

Characterization of left ventricular non-compaction cardiomyopathy

R Lorca, M Martín, I Pascual, A Astudillo… - Journal of Clinical …, 2020 - mdpi.com
Left ventricle non-compaction cardiomyopathy (LVNC) has gained great interest in recent
years, being one of the most controversial cardiomyopathies. There are several open …

Left ventricular noncompaction cardiomyopathy: updated review

DU Udeoji, KJ Philip, RP Morrissey… - Therapeutic …, 2013 - journals.sagepub.com
The first case of noncompaction was described in 1932 after an autopsy performed on a
newborn infant with aortic atresia/coronary–ventricular fistula. Isolated noncompaction …