[HTML][HTML] Identification of interaction partners of the cytosolic polyproline region of CD95 ligand (CD178)

MP Ghadimi, R Sanzenbacher, B Thiede, J Wenzel… - FEBS letters, 2002 - Elsevier
The CD95/Fas/Apo-1 ligand (CD95L, CD178) induces apoptosis through the death receptor
CD95. CD95L was also described as a co-stimulatory receptor for T-cell activation in mice in …

[HTML][HTML] Multiple interactions of the cytosolic polyproline region of the CD95 ligand: hints for the reverse signal transduction capacity of a death factor

J Wenzel, R Sanzenbacher, M Ghadimi, M Lewitzky… - FEBS letters, 2001 - Elsevier
The CD95/Fas/Apo-1 ligand is expressed on activated lymphocytes, NK cells, platelets,
certain immune-privileged cells and some tumor cells and induces apoptosis through the …

The CD95 (Fas/APO-1) receptor is phosphorylatedin vitro andin vivo and constitutively associates with several cellular proteins

G Gradl, P Grandison, E Lindridge, Y Wang, J Watson… - Apoptosis, 1996 - Springer
Abstract Different CD95 (Fas/APO-1) isoforms and phosphory lated CD95 species were
identified in human T and B cell lines. We had shown previously that the CD95 intracellular …

[HTML][HTML] CD95 stimulation results in the formation of a novel death effector domain protein-containing complex

IN Lavrik, T Mock, A Golks, JC Hoffmann… - Journal of Biological …, 2008 - ASBMB
Stimulation of CD95 (APO-1/Fas) by its natural ligand CD95L (APO-1L/FasL) leads to the
formation of the death-inducing signaling complex. Here we report that upon CD95 …

Isolation and analysis of components of CD95 (APO-1/Fas) death-inducing signaling complex

C Scaffidi, PH Krammer, ME Peter - Methods, 1999 - Elsevier
CD95 (APO-1/Fas) is an apoptosis-inducing receptor belonging to the tumor necrosis factor
receptor superfamily. Multimerization of CD95 leads to instant recruitment of the signaling …

CD95 (APO-1/Fas)-associating signalling proteins.

ME Peter, FC Kischkel, S Hellbardt… - Cell death and …, 1996 - europepmc.org
The CD95 (APO-1/Fas) receptor has attracted great interest in recent years because it
transduces an apoptotic signal in a variety of different tissues. CD95 belongs to the …

[HTML][HTML] Identification and characterization of a ligand-independent oligomerization domain in the extracellular region of the CD95 death receptor

G Papoff, P Hausler, A Eramo, MG Pagano… - Journal of Biological …, 1999 - ASBMB
The CD95 death receptor plays an important role in several physiological and pathological
apoptotic processes involving in particular the immune system. CD95 ligation leads to …

Principles and mechanisms of CD95 activation

H Wajant - Biological chemistry, 2014 - degruyter.com
Abstract CD95 (Apo1/Fas) has been originally identified as the target of cell death-inducing
antibodies. The recognition of CD95 as an apoptosis-triggering receptor represents one of …

Molecular ordering of the initial signaling events of CD95

A Algeciras-Schimnich, L Shen… - … and cellular biology, 2002 - Am Soc Microbiol
Binding of either ligand or agonistic antibodies to the death receptor CD95 (APO-1/Fas)
induces the formation of the death-inducing signaling complex (DISC). We now show that …

A novel protein (Fbf-1) that binds to CD95/APO-1/FAS and shows sequence similarity to trichohyalin and plectin

T Schmidt, H Karsunky, B Fraß, W Baum… - … et Biophysica Acta (BBA …, 2000 - Elsevier
The Fas/Apo-1/CD95 cell surface receptor belongs to the TNF receptor family of cell death
inducing molecules. A number of cytosolic adapter proteins that mediate signal transduction …