Temporal profiling of the secretome during adipogenesis in humans
J Zhong, SA Krawczyk, R Chaerkady… - Journal of proteome …, 2010 - ACS Publications
Adipose tissue plays a key role as a fat-storage depot and as an endocrine organ. Although
mouse adipogenesis has been studied extensively, limited studies have been conducted to …
mouse adipogenesis has been studied extensively, limited studies have been conducted to …
[HTML][HTML] Characterization of the human visceral adipose tissue secretome
G Alvarez-Llamas, E Szalowska, MP de Vries… - Molecular & Cellular …, 2007 - ASBMB
Adipose tissue is an endocrine organ involved in storage and release of energy but also in
regulation of energy metabolism in other organs via secretion of peptide and protein …
regulation of energy metabolism in other organs via secretion of peptide and protein …
[HTML][HTML] In-depth analysis of the adipocyte proteome by mass spectrometry and bioinformatics
Adipocytes are central players in energy metabolism and the obesity epidemic, yet their
protein composition remains largely unexplored. We investigated the adipocyte proteome by …
protein composition remains largely unexplored. We investigated the adipocyte proteome by …
[HTML][HTML] Identification and validation of novel adipokines released from primary human adipocytes
S Lehr, S Hartwig, D Lamers, S Famulla… - Molecular & cellular …, 2012 - ASBMB
Adipose tissue is a major endocrine organ, releasing signaling and mediator proteins,
termed adipokines, via which adipose tissue communicates with other organs. Expansion of …
termed adipokines, via which adipose tissue communicates with other organs. Expansion of …
Adipokines: a treasure trove for the discovery of biomarkers for metabolic disorders
S Lehr, S Hartwig, H Sell - PROTEOMICS–Clinical Applications, 2012 - Wiley Online Library
Adipose tissue is a major endocrine organ, releasing signaling and mediator proteins,
termed adipokines, via which adipose tissue communicates with other organs. Expansion of …
termed adipokines, via which adipose tissue communicates with other organs. Expansion of …
Secretome analysis of rat adipose tissues shows location-specific roles for each depot type
Obesity prevalence is reaching pandemic proportions becoming a major public health threat
for many industrialized nations. It is especially worrying as it causes a higher risk of …
for many industrialized nations. It is especially worrying as it causes a higher risk of …
Temporal profiling of the adipocyte proteome during differentiation using a five-plex SILAC based strategy
H Molina, Y Yang, T Ruch, JW Kim… - Journal of proteome …, 2009 - ACS Publications
The adipose tissue has important secretory and endocrine functions in humans. The
regulation of adipocyte differentiation has been actively pursued using transcriptomic …
regulation of adipocyte differentiation has been actively pursued using transcriptomic …
Functional annotation of the human fat cell secretome
I Dahlman, M Elsen, N Tennagels, M Korn… - … of physiology and …, 2012 - Taylor & Francis
Contex t: Recent secretome analyses suggest that human fat cells secrete hundreds of
proteins (adipokines). Objective: We made an overall analysis of their potential functional …
proteins (adipokines). Objective: We made an overall analysis of their potential functional …
Characterization of the human adipocyte proteome and reproducibility of protein abundance by one-dimensional gel electrophoresis and HPLC− ESI− MS/MS
Abnormalities in adipocytes play an important role in various conditions, including the
metabolic syndrome, type 2 diabetes mellitus and cardiovascular disease, but little is known …
metabolic syndrome, type 2 diabetes mellitus and cardiovascular disease, but little is known …
[HTML][HTML] Secretome of adipose tissue as the key to understanding the endocrine function of adipose tissue
D Pogodziński, L Ostrowska… - International journal of …, 2022 - mdpi.com
The prevalence of obesity has reached pandemic levels and is becoming a serious health
problem in developed and developing countries. Obesity is associated with an increased …
problem in developed and developing countries. Obesity is associated with an increased …