Paclitaxel (PTX) is efficacious in treating various solid tumors. However, the severe adverse
effects of its present formulation (Cremophor EL and ethanol) and the development of drug …

To fully make use of the synergism between paclitaxel and curcumin (CUR) in cancer
treatment, carrier made from CUR derivative was synthesized and used to deliver paclitaxel …

Purpose Polymeric micelles are attractive nanocarriers for tumor-targeted delivery of
paclitaxel (PTX). High antitumor efficacy and low toxicity require that PTX mainly …

Multi-drug chemotherapy has been one of the most popular strategies for the treatment of
malignant tumors, and has achieved desirable therapeutic outcomes. The objective of the …

The objective of this study was to prepare curcumin‐loaded mixed Soluplus/TPGS micelles
(Cur‐TPGS‐PMs) for oral administration. The Cur‐TPGS‐PMs showed a mean size of …

Curcumin is an effective and safe anticancer agent, but its hydrophobicity inhibits its clinical
application. Nanotechnology provides an effective method to improve the water solubility of …

To develop injectable formulation and improve the stability of curcumin (Cur), Cur was
encapsulated into monomethyl poly (ethylene glycol)-poly (ε-caprolactone)-poly …

Background: Paclitaxel (PTX) has been clinically used for several years due to its good
therapeutic effect against cancers. Its poor water-solubility, non-selectivity, high cytotoxicity …

Nanoscale polymeric micelles have promising applications as drug delivery systems (DDS).
In this work, to improve the anti-tumor activity and eliminate toxicity of the commercial …

Multidrug resistance (MDR) remains a significant impediment to chemotherapy during
cancer therapy. In this study, the amphiphilic biomaterials PEI-TOS and HA-QU were …