Background With the introduction of targeted therapies, there has been a growing need for
non-invasive imaging methods which accurately evaluate therapeutic effects and overcome …

Purpose: In order to detect an early response to anti-angiogenic therapy, this study aims at
analyzing specific effects of a sorafenib-based regime on intra-tumoral D-CEUS flow …

PURPOSE We aimed to assess the feasibility, efficacy and safety of a local application of
sorafenib within a conventional transarterial chemoembolization in the VX-2 tumor-bearing …

Purpose: To investigate dynamic contrast-enhanced magnetic resonance imaging (DCE-
MRI) with macromolecular contrast media (MMCM) to monitor the effects of the multikinase …

OBJECTIVE. The purpose of this study was to investigate with immunohistochemical
validation whether dynamic contrast-enhanced MRI with small-molecule contrast medium is …

Aim The aim of this study was to assess the role of dynamic contrast-enhanced perfusion
computed tomography (pCT) imaging in the early detection of blood flow changes related to …

Objectives To investigate whether hepatic perfusion CT yields early imaging biomarkers
predictive of the prognosis of hepatocellular carcinoma (HCC) patients treated with …

Background Targeted therapies are of increasing clinical importance and classic radiologic
therapy response-criteria often fail to detect early therapeutic response or failure. For …

Aims: To evaluate the sonographic changes observed in hepatocellular carcinoma (HCC)
post antiangiogenic treatment with sorafenib. Patients and methods: Twenty one …

Objective To determine the total Apparent Diffusion Coefficient (ADC), the pure Diffusion
coefficient (D) and the perfusion fraction (f) in advanced hepatocellular carcinoma (HCC) …