Clinical features of LRP4/agrin‐antibody–positive myasthenia gravis: A multicenter study

MH Rivner, BM Quarles, JX Pan, Z Yu… - Muscle & …, 2020 - Wiley Online Library
Introduction Our aim in this study was to identify the prevalence and clinical characteristics of
LRP4/agrin‐antibody–positive double‐seronegative myasthenia gravis (DNMG). Methods …

Anti‐LRP4 autoantibodies in Chinese patients with myasthenia gravis

Y Li, Y Zhang, G Cai, D He, Q Dai, Z Xu… - Muscle & nerve, 2017 - Wiley Online Library
Introduction We assessed antibodies against low‐density lipoprotein receptor‐related
protein 4 (LRP4‐Ab) in a Chinese population with myasthenia gravis (MG). Methods Serum …

Agrin and LRP4 antibodies as new biomarkers of myasthenia gravis

M Yan, GL Xing, WC Xiong, L Mei - Annals of the New York …, 2018 - Wiley Online Library
Myasthenia gravis (MG) is a common disorder that affects the neuromuscular junction. It is
caused by antibodies against acetylcholine receptor and muscle‐specific tyrosine kinase; …

A comprehensive analysis of the epidemiology and clinical characteristics of anti-LRP4 in myasthenia gravis

P Zisimopoulou, P Evangelakou, J Tzartos… - Journal of …, 2014 - Elsevier
Double-seronegative myasthenia gravis (dSN-MG, without detectable AChR and MuSK
antibodies) presents a serious gap in MG diagnosis and understanding. Recently …

Screening for lipoprotein receptor-related protein 4-, agrin-, and titin-antibodies and exploring the autoimmune spectrum in myasthenia gravis

I Cordts, N Bodart, K Hartmann, K Karagiorgou… - Journal of …, 2017 - Springer
In autoimmune myasthenia gravis (MG), the identification of antibodies and characterization
of serological subgroups is of great importance for diagnosis and management of the …

Autoantibodies to lipoprotein-related protein 4 in patients with double-seronegative myasthenia gravis

B Zhang, JS Tzartos, M Belimezi, S Ragheb… - Archives of …, 2012 - jamanetwork.com
Objectives To determine whether patients with myasthenia gravis (MG) have serum
antibodies to lipoprotein-related protein 4 (LRP4), a newly identified receptor for agrin that is …

Characterization of LRP4/Agrin antibodies from a patient with myasthenia gravis

Z Yu, M Zhang, H Jing, P Chen, R Cao, J Pan, B Luo… - Neurology, 2021 - AAN Enterprises
Background and Objective To determine whether human anti-LRP4/agrin antibodies are
pathogenic in mice and to investigate underpinning pathogenic mechanisms. Methods …

Anti-LRP4 autoantibodies in AChR-and MuSK-antibody-negative myasthenia gravis

A Pevzner, B Schoser, K Peters, NC Cosma… - Journal of …, 2012 - Springer
Myasthenia gravis (MG) is an autoimmune disorder characterized by a defect in synaptic
transmission at the neuromuscular junction causing fluctuating muscle weakness with a …

[HTML][HTML] Antibodies against low-density lipoprotein receptor–related protein 4 induce myasthenia gravis

C Shen, Y Lu, B Zhang, D Figueiredo… - The Journal of …, 2013 - Am Soc Clin Investig
Myasthenia gravis (MG) is the most common disorder affecting the neuromuscular junction
(NMJ). MG is frequently caused by autoantibodies against acetylcholine receptor (AChR) …

Autoantibodies to low‐density lipoprotein receptor–related protein 4 in myasthenia gravis

O Higuchi, J Hamuro, M Motomura… - Annals of …, 2011 - Wiley Online Library
Myasthenia gravis (MG) is an autoimmune disease of the neuromuscular junction, where
acetylcholine receptor (AChR), muscle‐specific kinase (MuSK), and low‐density lipoprotein …