Antitumor Activity and Underlying Mechanisms of Ganopoly, The Refined Polysaccharides Extracted from Ganoderma Lucidum, in Mice

Y Gao, H Gao, E Chan, W Tang, A Xu… - Immunological …, 2005 - Taylor & Francis
Ganopoly is an aqueous polysaccharide fraction extracted from G. lucidum by patented
biochemical technique and has been marketed as an over-the-counter product for chronic …

A Phase I/II Study of a Ganoderma lucidum (Curt.: Fr.) P. Karst. Extract (Ganopofy) in Patients with Advanced Cancer

Y Gao, S Zhou, G Chen, X Dai… - International Journal of …, 2002 - dl.begellhouse.com
In vitro and animal studies have established that the polysaccharide fractions of Ganoderma
lucidum have potential antitumor activity and inhibitory effect on tumor metastasis. Ganopoly …

Effects of Ganopoly® (A Ganoderma lucidum Polysaccharide Extract) on the Immune Functions in Advanced‐Stage Cancer Patients

Y Gao, S Zhou, W Jiang, M Huang… - Immunological …, 2003 - Taylor & Francis
Preclinical studies have established that the Ganoderma lucidum polysaccharide (GLPS)
fractions have potent anti‐tumor activity, which has been associated with the immuno …

Studies on the immuno-modulating and antitumor activities of Ganoderma lucidum (Reishi) polysaccharides: functional and proteomic analyses of a fucose-containing …

YY Wang, KH Khoo, ST Chen, CC Lin, CH Wong… - Bioorganic & medicinal …, 2002 - Elsevier
A fucose-containing glycoprotein fraction which stimulates spleen cell proliferation and
cytokine expression has been identified from the water-soluble extract of Ganoderma …

Antitumor and Immunomodulatory Effects of Polysaccharides from Broken-Spore of Ganoderma lucidum

PY Wang, XL Zhu, ZB Lin - Frontiers in pharmacology, 2012 - frontiersin.org
The antitumor and immunomodulatory activity of broken-spore of Ganoderma lucidum
polysaccharides (Gl-BSP) were investigated in vivo and in vitro. It was showed that Gl-BSP …

Ganoderma lucidum polysaccharide (GLP) enhances antitumor immune response by regulating differentiation and inhibition of MDSCs via a CARD9-NF-κB-IDO …

Y Wang, X Fan, X Wu - Bioscience Reports, 2020 - portlandpress.com
A homogeneous polysaccharide (GLP), with an average molecular weight of 4.44× 104 Da,
was isolated and purified from the fruiting bodies of Ganoderma lucidum. In this work, we …

Ganoderma lucidum Polysaccharides: Immunomodulation and Potential Anti-Tumor Activities

Z Xu, X Chen, Z Zhong, L Chen… - The American journal of …, 2011 - World Scientific
Ganoderma lucidum (G. lucidum), a basidiomycete white rot fungus, has long been
prescribed to prevent and treat various human diseases, particularly in China, Japan, and …

GLIS, a bioactive proteoglycan fraction from Ganoderma lucidum, displays anti-tumour activity by increasing both humoral and cellular immune response

J Zhang, Q Tang, C Zhou, W Jia, L Da Silva… - Life sciences, 2010 - Elsevier
AIMS: Ganoderma lucidum, a traditional Chinese medicine, is well known as a modulator of
functions of the immune system as well as an anti-tumour agent. However, its active …

Immunomodulatory activities of polysaccharides from Ganoderma on immune effector cells

L Ren, J Zhang, T Zhang - Food Chemistry, 2021 - Elsevier
Polysaccharides are the most abundant bioactive compounds in Ganoderma and have been
widely used as dietary supplements in traditional Chinese medicine for thousands of years …

Immunomodulation of RAW264. 7 macrophages by GLIS, a proteopolysaccharide from Ganoderma lucidum

Z Ji, Q Tang, J Zhang, Y Yang, W Jia, Y Pan - Journal of …, 2007 - Elsevier
The immunomodulatory effect of Ganoderma lucidum immunomodulating substance (GLIS)
on macrophages has been investigated as part of on-going research into the anti-cancer …