[HTML][HTML] RNA sequencing reveals the expression profiles of circRNA and indicates that circDDX17 acts as a tumor suppressor in colorectal cancer

XN Li, ZJ Wang, CX Ye, BC Zhao, ZL Li… - Journal of Experimental & …, 2018 - Springer
Abstract Background Circular RNA (circRNA) is a novel class of noncoding RNAs with
functions in various pathophysiological activities. However, the expression profiles and …

[HTML][HTML] CircEZH2/miR-133b/IGF2BP2 aggravates colorectal cancer progression via enhancing the stability of m6A-modified CREB1 mRNA

B Yao, Q Zhang, Z Yang, F An, H Nie, H Wang, C Yang… - Molecular cancer, 2022 - Springer
Background Aberrant expression of circular RNAs (circRNAs) contributes to the initiation
and progression of human malignancies, but the underlying mechanisms remain largely …

[HTML][HTML] CircRNA_0000392 promotes colorectal cancer progression through the miR-193a-5p/PIK3R3/AKT axis

H Xu, Y Liu, P Cheng, C Wang, Y Liu, W Zhou… - Journal of Experimental …, 2020 - Springer
Abstract Background Circular RNAs (circRNAs), important members of the noncoding RNA
family, have been recently revealed to play a role in the pathogenic progression of diseases …

Hsa_circ_101555 functions as a competing endogenous RNA of miR-597-5p to promote colorectal cancer progression

Z Chen, R Ren, D Wan, Y Wang, X Xue, M Jiang… - Oncogene, 2019 - nature.com
CircRNAs have been reported to exert momentous roles in regulating pathophysiological
process and guiding clinical diagnosis and treatment in colorectal cancer (CRC). However …

[HTML][HTML] CircIL4R activates the PI3K/AKT signaling pathway via the miR-761/TRIM29/PHLPP1 axis and promotes proliferation and metastasis in colorectal cancer

T Jiang, H Wang, L Liu, H Song, Y Zhang, J Wang… - Molecular Cancer, 2021 - Springer
Background Accumulating studies have revealed that aberrant expression of circular RNAs
(circRNAs) is widely involved in the tumorigenesis and progression of malignant cancers …

[HTML][HTML] Circular RNA circCTNNA1 promotes colorectal cancer progression by sponging miR-149-5p and regulating FOXM1 expression

P Chen, Y Yao, N Yang, L Gong, Y Kong, A Wu - Cell death & disease, 2020 - nature.com
Circular RNAs (circRNAs) are an emerging class of non-coding RNAs, identified to
participate in multiple malignancies. Nevertheless, the clinical significance, biological …

Comprehensive profile of differentially expressed circular RNAs reveals that hsa_circ_0000069 is upregulated and promotes cell proliferation, migration, and invasion …

J Guo, W Feng, J Shao, L Wan, M Huang… - OncoTargets and …, 2016 - Taylor & Francis
Background Nowadays, despite great progress in cancer research, the detailed
mechanisms of colorectal cancer (CRC) are still poorly understood. Circular RNAs …

CircRNA_100290 promotes colorectal cancer progression through miR-516b-induced downregulation of FZD4 expression and Wnt/β-catenin signaling

G Fang, BL Ye, BR Hu, XJ Ruan, YX Shi - Biochemical and biophysical …, 2018 - Elsevier
Accumulating evidence indicates that circular RNAs (circRNA) exert crucial functions in the
development and advance of cancers. CircRNA_100290 has been reported to promote …

Noncoding effects of circular RNA CCDC66 promote colon cancer growth and metastasis

KY Hsiao, YC Lin, SK Gupta, N Chang, L Yen, HS Sun… - Cancer research, 2017 - AACR
Circular RNA (circRNA) is a class of noncoding RNA whose functions remain mostly
unknown. Recent studies indicate circRNA may be involved in disease pathogenesis, but …

[HTML][HTML] A 3-circular RNA signature as a noninvasive biomarker for diagnosis of colorectal cancer

D Ye, S Wang, Y Huang, P Chi - Cancer cell international, 2019 - Springer
Abstract Background Circular RNAs (circRNAs), a novel type of noncoding RNAs, play
critical roles in the initiation and progression of cancer. Emerging studies also shows that …