Genetic factors play an important role in the aetiology of bipolar affective disorder (BP). So
far, results of linkage studies have been largely disappointing. We have searched for a …

Despite strong evidence for genetic involvement in the etiology of affective disorders (from
twin adoption and family studies), linkage and association methodologies are still exploring …

Based on the dopaminergic hypothesis, the dopamine D1 receptor gene (DRD1) is
considered to be a good candidate gene involved in the susceptibility of bipolar disorder …

The dopamine D3 receptor gene (DRD3) is a candidate gene in psychiatric disorders,
including affective disorders. The D3 receptor is characterized by a different tissue …

Association analysis of candidate genes may represent a strategy for clarifying the genetic
components involved in bipolar disorder. Polymorphism at dopamine receptor genes DRD2 …

Several lines of evidence point to a role for dopamine in mood disorders and, in particular, in
bipolar disorders. In line with a considerable amount of evidence, the dopamine D1 receptor …

Convincing evidence for a genetic component in the etiology of affective disorders (AD),
including bipolar affective disorder (BPAD) and unipolar affective disorder (UPAD), is …

We selected 83 patients with bipolar disorder type I or unipolar recurrent major depression
and 71 healthy controls for genetic analysis of the tyrosine hydroxylase and the dopamine …

Genetic factors may be associated with disease subtype as well as susceptibility. We have
therefore typed polymorphisms at the serotonin transporter, dopamine receptor, tryptophan …

A variety of studies have reported possible genetic associations between bipolar affective
disorder and different loci using relative risk (case-control) comparisons. An alternative …