[HTML][HTML] Healthspan and neural aging: Merging the exposome and one environmental health-From molecular mechanisms to epidemiology

MA Ottinger, GJ Harry, K Malecki… - Frontiers in Aging …, 2023 - frontiersin.org
Aging begins during development and establishes a framework for later events. The process
occurs through the lifespan and is influenced by individual genetics and life events. Such life …

[HTML][HTML] Integrating environment and aging research: opportunities for synergy and acceleration

KMC Malecki, JK Andersen, AM Geller… - Frontiers in aging …, 2022 - frontiersin.org
Despite significant overlaps in mission, the fields of environmental health sciences and
aging biology are just beginning to intersect. It is increasingly clear that genetics alone does …

[HTML][HTML] The chemical exposome of human aging

BB Misra - Frontiers in Genetics, 2020 - frontiersin.org
Aging is an inevitable biological phenomenon displayed by single cells and organs to entire
organismal systems. Aging as a biological process is characterized as a progressive decline …

[HTML][HTML] Exposome and unhealthy aging: environmental drivers from air pollution to occupational exposures

T Pandics, D Major, V Fazekas-Pongor, Z Szarvas… - Geroscience, 2023 - Springer
The aging population worldwide is facing a significant increase in age-related non-
communicable diseases, including cardiovascular and brain pathologies. This …

An update in toxicology of ageing

L Rackova, M Mach, Z Brnoliakova - Environmental Toxicology and …, 2021 - Elsevier
The field of ageing research has been rapidly advancing in recent decades and it had
provided insight into the complexity of ageing phenomenon. However, as the organism …

New Directions in Geroscience: Integrating Social and Behavioral Drivers of Biological Aging

L Nielsen, AL Marsland, EJ Hamlat… - Psychosomatic …, 2024 - journals.lww.com
The “geroscience hypothesis” posits that slowing the physiological processes of aging
would lead to delayed disease onset and longer healthspan and lifespan. This shift from a …

Aging hallmarks and progression and age-related diseases: a landscape view of research advancement

R Tenchov, JM Sasso, X Wang… - ACS Chemical …, 2023 - ACS Publications
Aging is a dynamic, time-dependent process that is characterized by a gradual accumulation
of cell damage. Continual functional decline in the intrinsic ability of living organisms to …

[HTML][HTML] The intersection between toxicology and aging research: A toxic aging coin perspective

JP Wise Jr - Frontiers in Aging, 2022 - frontiersin.org
We are imminently faced with the challenges of an increasingly aging population and longer
lifespans due to improved health care. Concomitantly, we are faced with ubiquitous …

[HTML][HTML] Biological age and environmental risk factors for dementia and stroke: Molecular mechanisms

P Knobel, R Litke, CV Mobbs - Frontiers in Aging Neuroscience, 2022 - frontiersin.org
Since the development of antibiotics and vaccination, as well as major improvements in
public hygiene, the main risk factors for morbidity and mortality are age and chronic …

[HTML][HTML] Sociobiological interactions in brain health: from disparities to social epigenomics

H Santamaria-Garcia, M Corley… - Frontiers in Aging …, 2024 - frontiersin.org
Critical environmental factors like physical threats, air pollution, and infections, alongside
social determinants of health (SDH)(Ibáñez et al., 2023) such as social disparities …