Effects of sacubitril/valsartan on exercise capacity: a prognostic improvement that starts during uptitration
M Mapelli, I Mattavelli, S Paolillo, E Salvioni… - European Journal of …, 2023 - Springer
Purpose Sacubitril/valsartan is a mainstay of the treatment of heart failure with reduced
ejection fraction (HFrEF); however, its effects on exercise performance yielded conflicting …
ejection fraction (HFrEF); however, its effects on exercise performance yielded conflicting …
Sacubitril/valsartan vs. standard medical therapy on exercise capacity in HFrEF patients
A Campanile, V Visco, S De Carlo, GJ Ferruzzi… - Life, 2023 - mdpi.com
Sacubitril/valsartan (Sac/Val) reduces mortality in patients with heart failure with reduced
ejection fraction (HFrEF) compared to enalapril. However, its effects on functional capacity …
ejection fraction (HFrEF) compared to enalapril. However, its effects on functional capacity …
Early effects of sacubitril/valsartan on exercise tolerance in patients with heart failure with reduced ejection fraction
G Vitale, G Romano, A Di Franco, G Caccamo… - Journal of clinical …, 2019 - mdpi.com
Background. Sacubitril/valsartan in heart failure (HF) with reduced ejection fraction (HFrEF)
was shown to be superior to enalapril in reducing the risk of death and hospitalization for …
was shown to be superior to enalapril in reducing the risk of death and hospitalization for …
Sacubitril/valsartan versus enalapril on exercise capacity in patients with heart failure with reduced ejection fraction: A randomized, double-blind, active-controlled …
Background Sacubitril/valsartan reduces mortality in patients with heart failure with reduced
ejection fraction (HFrEF) when compared with enalapril. However, it is unknown the effect of …
ejection fraction (HFrEF) when compared with enalapril. However, it is unknown the effect of …
Sacubitril/valsartan and short-term changes in the 6-minute walk test: A pilot study
P Beltran, P Palau, E Dominguez, M Faraudo… - International journal of …, 2018 - Elsevier
Background Impaired exercise capacity is the most disabling symptom in patients with heart
failure with reduced ejection fraction (HFrEF). Despite sacubitril/valsartan showing reduced …
failure with reduced ejection fraction (HFrEF). Despite sacubitril/valsartan showing reduced …
Dose-response to sacubitril/valsartan in patients with heart failure and reduced ejection fraction
Background Doses of sacubitril/valsartan (Sac/Val) achieved in clinical trials of heart failure
with reduced ejection fraction (HFrEF) are often not reached in clinical practice. Objectives …
with reduced ejection fraction (HFrEF) are often not reached in clinical practice. Objectives …
Effects of sacubitril/valsartan on functional status and exercise capacity in real-world patients
CW Lau, P Martens, S Lambeets, M Dupont… - Acta …, 2019 - Taylor & Francis
Background: Sacubitril/valsartan significantly reduced heart failure (HF) hospitalisations and
mortality in the PARADIGM-HF-trial. However real-world data on symptomatic and functional …
mortality in the PARADIGM-HF-trial. However real-world data on symptomatic and functional …
Comparison of the effect of sacubitril/valsartan on left ventricular systolic function in patients with non-ischaemic and ischaemic cardiomyopathy
A Ioannou, S Metaxa, S Simon, AKJ Mandal… - … Drugs and Therapy, 2020 - Springer
Purpose Sacubitril/valsartan has been demonstrated to improve prognosis and outcomes in
heart failure with reduced ejection fraction (HFrEF) patients. We sought to compare the …
heart failure with reduced ejection fraction (HFrEF) patients. We sought to compare the …
Sacubitril/valsartan can improve exercise performance in systolic chronic heart failure patients: a case report
M Mapelli, C Vignati, S Paolillo… - Current Medical …, 2019 - Taylor & Francis
Objective: The cardiopulmonary exercise test (CPET) provides functional prognostic
parameters for patients with chronic heart failure (CHF), such as peak volume of oxygen …
parameters for patients with chronic heart failure (CHF), such as peak volume of oxygen …
Sacubitril/valsartan use in a real-world population of patients with heart failure and reduced ejection fraction
M Mapelli, E Salvioni, F de Martino… - Journal of …, 2020 - journals.lww.com
Aims Practice guidelines recommend sacubitril/valsartan for heart failure with reduced
ejection fraction. The aim of our study was to describe the use of sacubitril/valsartan in real …
ejection fraction. The aim of our study was to describe the use of sacubitril/valsartan in real …
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