Frontotemporal dementia (FTD) causes progressive personality, behavior and/or language
disturbances and represents the second most common form of dementia under the age of …

Ubiquitin-immunoreactive neuronal inclusions composed of TAR DNA binding protein of 43
kDa (TDP-43) are a major pathological feature of frontotemporal lobar degeneration (FTLD …

Frontotemporal lobar degeneration (FTLD) with TDP-43-immunoreactive inclusions (FTLD–
TDP) is a neurodegenerative disease associated with clinical, genetic, and …

Transactive response DNA-binding protein 43 (TDP-43) is the pathological signature protein
in several neurodegenerative disorders, including the majority of frontotemporal lobar …

TAR DNA-binding protein of about 43 kDa (TDP-43) is the main ubiquitinated peptide in tau-
negative frontotemporal lobar degeneration (FTLD). TDP-43 is typically a nuclear protein …

Frontotemporal lobar degeneration (FTLD) has been subdivided based on the main
pathology found in the brains of affected individuals. When the primary pathology is …

TAR DNA-binding protein of 43 kDa (TDP-43) is the major component protein of inclusions
found in brains of patients with amyotrophic lateral sclerosis (ALS) and frontotemporal lobar …

Frontotemporal Dementia (FTD) and amyotrophic lateral sclerosis (ALS) are two
neurodegenerative diseases associated to mislocalization and aggregation of TAR DNA …

Abstract TAR DNA-binding protein (TDP-43) is a ubiquitously expressed nuclear protein,
which participates in a number of cellular processes and has been identified as the major …

TDP-43 is a multifunctional DNA/RNA-binding factor that has been implicated in the
regulation of neuronal plasticity. TDP-43 has also been identified as the major constituent of …