Although tumors tend to be associated with immune cells and inflammation, this immune
response often fails to eliminate the cancer and instead promotes cancer progression …

Despite the well-established role of CMTM6 in the stabilization of cell surface PD-L1 in
cancer cells, the mechanisms underlying CMTM6 expression and regulation are still largely …

Activating enhancer-binding protein-2α (AP-2α) regulates the expression of many cancer-
related genes. Here, we demonstrated a novel mechanism by which AP-2α up-regulated …

The transcription factor CCAAT/enhancer-binding protein α (C/EBPα) is a basic leucine
zipper transcription factor and is expressed in alveolar type II cells, alveolar macrophages …

Eukaryotic initiation factor 5A2 (eIF5A2) is overexpressed in many types of cancer, and
spermidine-mediated eIF5A hypusination (eIF5Ahpu) appears to be essential to most of …

The expansion of myeloid‐derived suppressor cells (MDSCs) correlates with tumorigenesis
in colorectal cancer (CRC). Here, we found a significant association between CD33+ MDSC …

Purpose The purpose of this study was to investigate the effect of human antigen R (HuR)
downregulation and the potential target genes of HuR on the progression of esophageal …

Macrophages in the tumor microenvironment respond to complex cytokine signals. How
these responses shape the phenotype of tumor-associated macrophages (TAMs) is …

Interactions between malignant tumors and the host immune system shape the course of
cancer progression. The molecular basis of such interactions is the subject of immense …

Nasopharyngeal carcinoma (NPC) is a common malignant epithelial tumor of the head and
neck that often exhibits local recurrence and distant metastasis. The molecular mechanisms …