The direct binding of platelets by bacteria is a postulated central mechanism in the
pathogenesis of endocarditis. To address the role of binding more definitively, we employed …

The direct binding of bacteria to platelets may be an important virulence mechanism in the
pathogenesis of infective endocarditis. We have previously described Staphylococcus …

The direct binding of bacteria to platelets is a postulated major interaction in the
pathogenesis of infective endocarditis. To identify bacterial components that mediate platelet …

Several lines of evidence indicate that platelets protect against endovascular infections such
as infective endocarditis (IE). It is highly likely that a principal mechanism of this platelet host …

There is growing evidence that platelets play an important role in the development of
infective endocarditis IE. This review focuses on interactions between bacteria and platelets …

The direct binding of bacteria to human platelets contributes to the pathogenesis of infective
endocarditis. Platelet binding by Streptococcus mitis strain SF100 is mediated in part by two …

Animal models of infective endocarditis (IE) induced by high-grade bacteremia revealed the
pathogenic roles of Staphylococcus aureus surface adhesins and platelet aggregation in the …

Abstract Background. The ability of Staphylococcus aureus to adhere to platelets and to
induce aggregation of platelets is considered to be a critical factor in S. aureus-associated …

The adherence of microorganisms to platelets previously immobilized on the
subendocardium in nonbacterial thrombotic endocarditis is considered an important …

Bacterium-platelet interactions at the cardiac valve surface represent an important initial step
in the induction of infective endocarditis (IE). This cell-cell interaction may play either a …