Ultra-small lipid nanoparticles promote the penetration of coenzyme Q10 in skin cells and counteract oxidative stress

SB Lohan, S Bauersachs, S Ahlberg… - European Journal of …, 2015 - Elsevier
UV irradiation leads to the formation of reactive oxygen species (ROS). An imbalance
between the antioxidant system and ROS can lead to cell damage, premature skin aging or …

Ultra-small NLC for improved dermal delivery of coenyzme Q10

JC Schwarz, N Baisaeng, M Hoppel, M Löw… - International journal of …, 2013 - Elsevier
Coenzyme Q10 (CoQ10) acts as an antioxidant in the skin and is frequently contained in anti-
aging products. In previous studies, it could be shown that nano-structured lipid carriers …

A comparative evaluation of coenzyme Q10-loaded liposomes and solid lipid nanoparticles as dermal antioxidant carriers

EH Gokce, E Korkmaz… - International journal …, 2012 - Taylor & Francis
Background The effective delivery of coenzyme Q10 (Q10) to the skin has several benefits in
therapy for different skin pathologies. However, the delivery of Q10 to deeper layers of skin …

The advantages of a novel CoQ10 delivery system in skin photo-protection

Y Yue, H Zhou, G Liu, Y Li, Z Yan, M Duan - International journal of …, 2010 - Elsevier
Skin photo-ageing induced by ultraviolet (UV) radiation is mainly ascribed to oxidative stress
and reactive oxygen species (ROS). Coenzyme Q10 (CoQ10) has been reported as a …

An overview on topical administration of carotenoids and coenzyme Q10 loaded in lipid nanoparticles

L de Souza Guedes, RM Martinez, NA Bou-Chacra… - Antioxidants, 2021 - mdpi.com
Carotenoids and coenzyme Q10 are naturally occurring antioxidant compounds that are
also found in human skin. These bioactive compounds have been the focus of considerable …

Nanostructured lipid carriers loaded with CoQ10: Effect on human dermal fibroblasts under normal and UVA-mediated oxidative conditions

F Brugè, E Damiani, C Puglia, A Offerta… - International journal of …, 2013 - Elsevier
Nanostructured lipid carriers (NLC) represent an emerging tool for drug delivery and are
characterized by important features which promote increased bioavailability and epithelial …

Nanoemulsions and topical creams for the safe and effective delivery of lipophilic antioxidant coenzyme Q10

M Kaci, A Belhaffef, S Meziane, G Dostert… - Colloids and Surfaces B …, 2018 - Elsevier
Emulsion-based delivery systems have been developed to increase the topical
bioavailability of lipophilic active compounds within skin membrane. The aim was to develop …

Lipid nanoparticles containing coenzyme Q10 for topical applications: An overview of their characterization

IDL Souza, V Saez, CRE Mansur - Colloids and Surfaces B: Biointerfaces, 2023 - Elsevier
The coenzyme Q10 is a compound widely used in pharmaceutical and cosmetic
formulations because it is a potent eliminator of free radicals, giving it antioxidant and anti …

Preparation and characterization of liposomal coenzyme Q10 for in vivo topical application

WC Lee, TH Tsai - International journal of pharmaceutics, 2010 - Elsevier
Coenzyme Q10 (CoQ10) is an endogenous cellular antioxidant that is used as a nutritional
supplement and for medicinal purposes. In recent in vivo investigations, cosmetically …

Coenzyme Q10 and retinaldehyde co-loaded nanostructured lipid carriers for efficacy evaluation in wrinkles

K Nayak, SS Katiyar, V Kushwah… - Journal of Drug Targeting, 2018 - Taylor & Francis
This study depicts coenzyme Q10 (CoQ10) and retinaldehyde (RAL) co-loaded
nanostructured lipid carriers (NLCs); having activity on different targets of photoageing …