Vitamin D regulates gene expression and affects target cell functions. IL-6 and IL-17A are
pro-inflammatory cytokines associated with MS pathogenesis. The aim of this study was to …

Multiple sclerosis (MS) is an inflammatory and autoimmune disease. Variety of different
genetics and environmental factors are involved in MS pathology. The epidemiological …

Objective To assess the effects of dietary vitamin D3 on proinflammatory (interleukin-17A [IL-
17A] and IL-6) and anti-inflammatory (IL-10) cytokines. Methods Our study was conducted …

Background & aims In our previous study, a Seesaw model was proposed for the fluctuation
of crucial anti-(IL-10) and pro-inflammatory (Il-6 & IL-17A) cytokines through vitamin D3. In …

Vitamin D is known to have immunomodulatory properties and its deficiency is identified as
an environmental risk factor for the development of autoimmune diseases, including multiple …

Vitamin D is known for its role in modulating calcium and phosphate homeostasis and is
implicated both in bone mineralization and immune system regulation. The immune …

Background Vitamin D has immunomodulatory effects in multiple sclerosis (MS). Vitamin D
acts through various mechanisms such as secretion of cytokines. Interleukin-17 (IL-17) is a …

Vitamin D deficiency is an environmental risk factor for MS, a Th17 cell-mediated
autoimmune disease that results in demyelination in the CNS. Therefore, we aimed to …

Background: Vitamin D is one of the considerable environmental factors exhibiting
immunomodulatory and anti-inflammatory effects. Objective: To conduct a systematic review …

Background: To investigate the possible association between serum 25 (OH) vitamin D 3
concentration and the severity of disease in Iranian patients with multiple sclerosis (MS) and …