Abstract Lipid-drug conjugates (LDC), which may also be addressed as lipoidal prodrug,
have the therapeutic actives chemically bound to a lipid moiety like fatty acids or …

Lipid drug conjugates (LDCs) are the chemical entities, which are commonly referred to as
lipoidal prodrug. They contain the bioactive molecules, covalently or non-covalently linked …

Hydrophilic drugs are preferred candidates for most routes of drug administration, because
of their enhanced solubility and dissolution under aqueous in vivo conditions. However, their …

A majority of studies involving prodrugs are directed to overcome low bioavailability of the
parent drug. The aim of this study is to increase the bioavailability of acyclovir (ACV) by …

Lipid–drug conjugates (LDCs) are drug molecules that have been covalently modified with
lipids. The conjugation of lipids to drug molecules increases lipophilicity and also changes …

The combination of lipid drug delivery systems with prodrugs offers several advantages
including improved pharmacokinetics, increased absorption, and facilitated targeting …

The oral route is the most widely accepted and commonly used route for administration.
However, this route may not be suitable for certain drug candidates which suffer from the …

Solid lipid nanoparticles are at the forefront of the rapidly developing field of nanotechnology
with several potential applications in drug delivery, clinical medicine and research, as well …

Solid Lipid Nanoparticles (SLNs) have attracted increasing scientific and commercial
attention as colloidal drug carriers during the last decade. They have emerged as a potential …

Lipid nanocarriers have recently emerged as a novel approach for oral drug administration
as the latest development of lipid-based drug delivery system. This chapter will focus in …