Implications of water channel proteins in selected neurological disorders: epilepsies, muscular dystrophies, amyotrophic lateral sclerosis, neuromyelitis optica …

I Benga, O Benga - Molecular Aspects of Medicine, 2012 - Elsevier
The aim of this article is to describe the roles of water channel proteins (WCPs) in some
neurological diseases in which the implications of these proteins became obvious in the …

Priorities in the discovery of the implications of water channels in epilepsy and duchenne muscular dystrophy.

I Benga - Cellular and Molecular Biology (Noisy-le-Grand …, 2006 - europepmc.org
In addition to the priority in the discovery of the first water channel protein in the red blood
cell membrane the group of Gheorghe Benga in Cluj-Napoca, Romania, also has a world …

Regulation, structure and function of brain aquaporin

Y Masato - Rinsho Shinkeigaku= Clinical Neurology, 2009 - europepmc.org
Discovery of aquaporin water channel proteins has provided insight into the molecular
mechanism of membrane water permeability. In mammalian brain, Aquaporin-4 (AQP4) is …

IMPLICATIONS OF WATER CHANNEL PROTEINS (AQUAPORINS AND RELATIVES) IN EPILEPSIES.

I Benga - Studia Universitatis Babes-Bolyai, Chemia, 2021 - search.ebscohost.com
The abundant evidence linking epilepsy with hydroelectrolytical changes in epilepsy
reported in the medical literature for over 9 decades is reviewed. Our work on this topic is …

Potential Role of Antibodies against Aquaporin-1 in Patients with Central Nervous System Demyelination

M Pechlivanidou, K Xenou, D Tzanetakos… - International Journal of …, 2023 - mdpi.com
Aquaporins (AQPs; AQP0–AQP12) are water channels expressed in many and diverse cell
types, participating in various functions of cells, tissues, and systems, including the central …

Aquaporins in neurological disorders

L Hirt, M Price, C Benakis… - Clinical and Translational …, 2018 - journals.sagepub.com
Aquaporins (AQPs) are water channel molecules that allow the passage of water through
the lipid bilayers of cell membranes. AQP1, AQP4 and AQP9 are expressed in the central …

Aquaporins: multifarious roles in brain

M Amiry-Moghaddam, EH Hoddevik… - …, 2010 - ibroneuroscience.org
Six years have elapsed since the publication of the Neuroscience Special Issue entitled
“Brain Water Homeostasis”(Agre et al., 2004). Several of the chapters in the latter Special …

Aquaporin-4 in neuromyelitis optica spectrum disorders: a target of autoimmunity in the central nervous system

Y Abe, M Yasui - Biomolecules, 2022 - mdpi.com
Since the discovery of a specific autoantibody in patients with neuromyelitis optica spectrum
disorder (NMOSD) in 2004, the water channel aquaporin-4 (AQP4) has attracted attention as …

Water movements in the brain: role of aquaporins

MJ Tait, S Saadoun, BA Bell… - TRENDS in …, 2008 - cell.com
About 80% of the brain is water. This review discusses the importance of the three brain
water-channel proteins (AQP1, AQP4, AQP9) in brain physiology. AQP1 is expressed in the …

Supramolecular aggregation of aquaporin‐4 is different in muscle and brain: correlation with tissue susceptibility in neuromyelitis optica

S Rosito, GP Nicchia, C Palazzo, A Lia… - Journal of Cellular …, 2018 - Wiley Online Library
Neuromyelitis optica (NMO) is an autoimmune demyelinating disease of the central nervous
system (CNS) caused by autoantibodies (NMO‐IgG) against the water channel aquaporin‐4 …