Introduction Although there are several FDA-approved treatments for Alzheimer's disease
(AD), only recently have disease-modifying therapies received approval for use in patients …

Inflammatory lesions in the central nervous system of patients with neuromyelitis optica are
characterized by infiltration of T cells and deposition of aquaporin-4-specific antibodies and …

Background Neuromyelitis optica (NMO), a severe demyelinating disease, represents itself
with optic neuritis and longitudinally extensive transverse myelitis. Serum NMO-IgG …

Abstract Aquaporin 4 (AQP4) is a water channel protein strongly expressed in the central
nervous system in perimicrovessel astrocyte foot processes, the glia limitans, and …

Aquaporins (AQPs) are water channel proteins robustly expressed in the central nervous
system (CNS). A number of previous studies described the cellular expression sites and …

Neuromyelitis optica (NMO) is thought to be caused by immunoglobulin G autoantibodies
(NMO‐IgG) against astrocyte water channel aquaporin‐4 (AQP4). A recent study (Hinson et …

Aquaporins (AQPs), transmembrane proteins allowing the passage of water and sometimes
other small solutes and molecules, are involved in autoimmune diseases including …

The current study presents a western blot assay showing good sensitivity (81%) and
specificity (97%) for detecting serum antibodies to Aquaporin-4 (AQP4) in patients with …

Neuromyelitis optica (NMO) is an inflammatory autoimmune demyelinating disease of the
central nervous system (CNS) which in autoantibodies produced by patients with NMO …

Abstract Aquaporin 4 (AQP4) is a protein highly expressed in the central nervous system
(CNS) and peripheral nervous system (PNS) as well as various other organs, whose …