Mechanisms underlying interferon-mediated host innate immunity during influenza A virus infection
C Chen, X Chi, Q Bai, J Chen - Sheng wu gong cheng xue bao …, 2015 - europepmc.org
Influenza A virus can create acute respiratory infection in humans and animals throughout
the world, and it is still one of the major causes of morbidity and mortality in humans …
the world, and it is still one of the major causes of morbidity and mortality in humans …
Influenza a virus regulates interferon signaling and its associated genes; MxA and STAT3 by cellular miR-141 to ensure viral replication
M Alalem, E Dabous, AM Awad, N Alalem, AA Guirgis… - Virology Journal, 2023 - Springer
The antiviral response against influenza A virus (IAV) infection includes the induction of the
interferon (IFN) signaling pathway, including activation of the STATs protein family …
interferon (IFN) signaling pathway, including activation of the STATs protein family …
Baicalin inhibits influenza virus A replication via activation of type I IFN signaling by reducing miR‑146a
R Li, L Wang - Molecular Medicine Reports, 2019 - spandidos-publications.com
Influenza virus A (IVA) is one of the predominant causative agents of the seasonal flu and
has become an important cause of morbidity worldwide. Great efforts have been paid to …
has become an important cause of morbidity worldwide. Great efforts have been paid to …
MicroRNA-200c-targeted contactin 1 facilitates the replication of influenza A virus by accelerating the degradation of MAVS
S Xu, L Han, Y Wei, B Zhang, Q Wang, J Liu… - PLoS …, 2022 - journals.plos.org
Influenza A viruses (IAVs) continuously challenge the poultry industry and human health.
Elucidation of the host factors that modulate the IAV lifecycle is vital for developing antiviral …
Elucidation of the host factors that modulate the IAV lifecycle is vital for developing antiviral …
NMI facilitates influenza A virus infection by promoting degradation of IRF7 through TRIM21
W Ouyang, M Cen, L Yang, W Zhang… - American Journal of …, 2021 - atsjournals.org
Acute respiratory infections caused by influenza A virus (IAV) spread widely and lead to
substantial morbidity and mortality. Host cell induction of type I interferon (IFN-I) plays a …
substantial morbidity and mortality. Host cell induction of type I interferon (IFN-I) plays a …
Dimethyl-Dioctadecyl-Ammonium Bromide/Poly (lactic acid) Nanoadjuvant Enhances the Immunity and Cross-Protection of an NM2e-Based Universal Influenza …
Y Gao, S Han, F Lu, Q Liu, J Yang, W Wang, Y Wang… - ACS …, 2024 - ACS Publications
For most frequent respiratory viruses, there is an urgent need for a universal influenza
vaccine to provide cross-protection against intra-and heterosubtypes. We previously …
vaccine to provide cross-protection against intra-and heterosubtypes. We previously …
Influenza A Infection Stimulates RIG-I and Enhances Effector Function of Primary Human NK Cells
Immune surveillance by natural killer (NK) cells and their recruitment to sites of inflammation
renders them susceptible to viral infection, potentially modulating their effector function …
renders them susceptible to viral infection, potentially modulating their effector function …
Identification of cellular microRNA-136 as a dual regulator of RIG-I-mediated innate immunity that antagonizes H5N1 IAV replication in A549 cells
L Zhao, J Zhu, H Zhou, Z Zhao, Z Zou, X Liu, X Lin… - Scientific reports, 2015 - nature.com
Abstract H5N1 influenza A virus (IAV) causes severe respiratory diseases and high mortality
rates in animals and humans. MicroRNAs are being increasingly studied to evaluate their …
rates in animals and humans. MicroRNAs are being increasingly studied to evaluate their …
Exploring the Inhibitory Effect of AgBiS2 Nanoparticles on Influenza Viruses
J Yang, L Yue, B Shen, Z Yang, J Shao, Y Miao… - International Journal of …, 2023 - mdpi.com
Influenza viruses are respiratory pathogens that are major threats to human health. Due to
the emergence of drug-resistant strains, the use of traditional anti-influenza drugs has been …
the emergence of drug-resistant strains, the use of traditional anti-influenza drugs has been …
Virus-like particle–mediated delivery of the RIG-I agonist M8 induces a type I interferon response and protects cells against viral infection
Virus-Like Particles (VLPs) are nanostructures that share conformation and self-assembly
properties with viruses, but lack a viral genome and therefore the infectious capacity. In this …
properties with viruses, but lack a viral genome and therefore the infectious capacity. In this …